What we do
Viruses and phage
- Purity and homogeneity of prep
- Assembly, contamination or storage problems
- Particle counting
- 3D structure
Ultrastructure and organelle morphology
- Ultrastructure of cells and tissue
- Organelle morphology
- Analysis of mutants and knockouts
- 3D structure
Nanoparticles and liposomes
- Size measurements
- Uni- vs multilamellar liposomes
- Membrane thickness
- Nanoparticle ultrastructure
Bacteria
- Bacterial ultrastructure
- Bacterial division defects
- 3D structure of bacterial components
- Nanoparticle binding and uptake
- Ultrastructure of biofilms
Proteins and complexes
- Purity and homogeneity of prep
- Conformation analysis
- Flexibility and range of movement
- High-resolutions 3D structure
- Optimisation and screening for regional facilities
Locating targets within samples
- Immunolabelling in resin
- Tokuyasu immunolabelling
- Correlative light and electron microscopy
- Light sheet fluorescence microscopy