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    Warwick Medical School

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    University of Warwick

    Biomedical Cell Biology


    cells under microscope
    John.Davey

    John Davey
    Head of Division of Biomedical Cell Biology

    The Division of Biomedical Cell Biology (BCB) carries out fundamental molecular and cellular research into biomedical problems.

    BCB explores a broad, integrated ‘systems’ understanding of the highly complex interactions between components of physiological systems at the molecular, cellular, tissue, organ and system levels. The division has research links with colleagues in WMS, Life Sciences and Systems Biology, as well as Chemistry, Physics, Computer Sciences, Complexity and Engineering.

    Contact

    Gemma Wild
    Divisional Secretary

    Tel: +44 (0)247 615 1154
    Email: G dot Wild at warwick dot ac dot uk

    Principal Investigators

    • Nick Carter Single molecule imaging (Research)
    • Robert Cross Mechanochemistry of kinesin and tubulin (Research)
    • Jacob Dalgaard DNA replication (Research)
    • John Davey Intracellular signalling through G proteins (Research)
    • Graham Ladds Modelling spatiotemporal control of cell signalling (Research)
    • Andrew McAinsh Mechanics of chromosome separation (Research)
    • Jonathan Millar Cell cycle control mechanisms (Research)
    • Masanori Mishima Mechanics and control of cytokinesis (Research)
    • Anne Straube Cytoskeletal dynamics and cell migration (Research)

    *** We are currently recruiting for new Group Leaders***

    Details for Full Professor level

    Details for Associate Professor level

     

    Research Areas

    • Chromosome Biology
    • Intracellular Signalling Networks
    • Mechanochemical Cell Biology
    • Warwick Insight
    • Funders and Funding Opportunities
    • BCB staff intranet

    Research News

    News

    BCB held their Inaugural Retreat, December 2011. More details

    Conferences and Workshops

    Seminars

    Our Next Seminar is on Wednesday 30 May 2012, Professor Jonathan Millar (Professor, Biomedical Cell Biology Division, University of Warwick), "Ordered S and M phases: threshold attainment or bi-stable switch?" at 1.30pm, CTU Building, Room T0.08/0.09

    Papers

    Shepperd, L.A., Meadows, J.C., Sochaj, A.M., Lancaster, T.C., Zou, J., Buttrick, G.J., Rappsilber, J., Hardwick, K.G. and Millar, J.B.A. (2012) Phospho-dependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint. Current Biology (in press).

    Steinacher R, Osman F, Dalgaard J.Z, Lorenz A, Whitby M.C. (2012) The DNA helicase Pfh1 promotes fork merging at replication termination sites to ensure genome stability. Genes and Development {In Press}

    Kaseda K, McAnish AD, Cross RA (2011) Dual pathway spindle assembley increases both the speed and the fidelity of mitosis. Biology Open doi: 10.1242/bio.2011012 Pdf of paper

    Grant BJ, Gheorghe DM, Zheng W, Alonso M, Huber G, Dlugosz M, McCammon JA, Cross RA (2011) Electrostatically Biased Binding of Kinesin to Microtubules. Plos Biology 9(11):e1001207 Pubmed abstract

    Samora CP, Mogessie B, Conway L, Ross JL, Straube A, McAinsh AD (2011) MAP4 and CLASP1 operate as a safety mechanism to maintain a stable spindle position in mitosis. Nature Cell Biology doi: 10.1038/ncb2297 Pubmed abstract

    Meadows JC, Shepphed LA, Vanoosthuys V, Lancaster TC, Sochaj AM, Buttrick GJ, Hardwick KG and Millar JB (2011) Spindle checkpoint silencing requires association of PP1 to both Spc7 and kinesin-8 motors. Developmental Cell 20, 739-750 Pubmed abstract

    Vengrova S (2011) DNA Repair and Human Health Book Details

    Vacancies

    We are always interested in hearing from motivated people keen to join the Division of Biomedical Cell Biology (PhD, Technician, Research Fellow, Group Leader). Please contact John Davey (Head of Division) on J.Davey@Warwick.ac.uk for an informal discussion.

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    Page contact: Hannah Poulton Last revised: Wed 23 May 2012
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