Background

Glycation in micro-organisms

• Glycation adducts in bacteria
• The enzymatic defence against glycation in bacteria
• The enzymatic defence against glycation in protozoans (malaria, trypanosoma and others)
• Glycation and the enzymatic defence against glycation in nematodes (C. elegans and others), tapeworms and flukes

Glycation in plants

• Glycation adducts in plants
• The enzymatic defence against glycation in plants

Glycation in animals

• Glycemic metabolism and glycation potential in mammals and birds

Glycation contribution to theories of ageing

• Overview: theories of ageing
• Glycation and telomere attrition theory
• Glycation and the free radical theory of ageing
• glycation and the wear-and-tear theory
• Assessing the experimental evidence

-  Drosophila melanogaster

-  Caenorhabditid elegans

-  Rodents

-  Human studies

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