Professor Jan Brosens

Jan Brosens

CONTACT   

Reproductive Health
University of Warwick
Coventry
CV4 7AL 		Tel: 024 7696 8704
Email: J.J.Brosens@warwick.ac.uk

 

BACKGROUND


Professor Jan Brosens' research centres on the role of steroid hormone signalling in the human endometrium, especially in the context of prevalent reproductive disorders, such as infertility, endometriosis and endometrial cancer. his major translational interest is focused on improving the management of miscarriage, the most common complication of pregnancy. He obtained a PhD from the University of London in 1999, working on the mechanisms underpinning the preparation of the lining of the womb (endometrium) for pregnancy, a process called decidualization. He was awarded a Wellcome Trust Clinical Scientist Fellowship in 1998, then joined Imperial College London as Chair of Reproductive Sciences in 2004 and became Chair of Reproductive Medicine in 2008. In May 2011 he was appointed as Chair of Obstetrics and Gynaecology at the University of Warwick.

SELECTED PUBLICATIONS


  • Kuroda K; Venkatakrishnan R; Salker MS; Lucas ES; haheen F; Kuroda M; Blanks A; Christian M; Quenby S; Brosens JJ. (2012) 'Induction of 11â-HSD 1 and Activation of Distinct Mineralocorticoid Receptor- and Glucocorticoid Receptor-Dependent Gene Networks in Decidualizing Human Endometrial Stromal Cells.' Molecular Endocrinology [article]
  • Koot YE; Teklenburg G; Salker MS; Brosens JJ; Macklon NS. (2012) 'Molecular aspects of implantation failure.' Biochimica et Biophysica Acta - Biomembranes 1822 (12), 1943 - 1950 [article]
  • Lee Y; Sooranna SR; Terzidou V; Christian M; Brosens J; Huhtinen K; Poutanen M; Barton G; Johnson MR; Bennett PR. (2012) 'Interactions between inflammatory signals and the progesterone receptor in regulating gene expression in pregnant human uterine myocytes.' Journal of Cellular and Molecular Medicine 16 (10), 2487 - 2503 [article]
  • Odiari EA; Mulla MJ; Sfakianaki AK; Paidas MJ; Stanwood NL; Gariepy A; Brosens JJ; Chamley LW; Abrahams VM. (2012) 'Pravastatin does not prevent antiphospholipid antibody-mediated changes in human first trimester trophoblast function.' Human Reproduction 27 (10), 2933 - 2940 [article]
  • Kuroda M; Kuroda K; Arakawa A; Fukumura Y; Kitade M; Kikuchi I; Kumakiri J; Matsuoka S; Brosens IA; Brosens JJ; Takeda S; Yao T. (2012) 'Histological assessment of impact of ovarian endometrioma and laparoscopic cystectomy on ovarian reserve.' Journal Of Obstetrics And Gynaecology 38 (9), 1187 - 1193 [article]

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