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Professor Judith Klein

 

Title   

Professor
 

Contact   

WMS - Translational Medicine
University of Warwick
Coventry
CV4 7AL
Tel: 02476 573 806
Email: J.Klein-Seetharaman@warwick.ac.uk
WebLink: http://www2.warwick.ac.uk/fac/med/staff/jklein/

Research Interests

I am an interdisciplinary researcher interested in the integration of diverse approaches to the study of proteins and lipids and potential applications in human health. Current research interests include (1) biophysics of membrane receptors (e.g. rhodopsin and other G protein coupled receptors, interferon gamma receptors, insulin receptor), (2) systems biology of protein-protein interactions, including host-pathogen interactions, (3) biological language modeling of proteins and lipids and (4) development of new approaches to promote life-style behaviour changes, e.g. weight loss.

Biography

Judith Klein-Seetharaman is Professor of Biomedicine and Systems Biology at the University of Warwick, jointly appointed by the Warwick Medical School, Division of Translational and Systems Medicine, and the Warwick Systems Biology Centre. Prior, she was tenured Associate Professor at the Department of Structural Biology at the University of Pittsburgh, USA, Professor in Biological Sciences at Royal Holloway University of London, UK, and held adjunct appointments at the Language Technologies Institute in the School of Computer Science at Carnegie Mellon University, USA, and the Research Centre Juelich, Germany, amongst others. She is currently an FP7 People Funded International Incoming Fellowship Awardee and holds grant from industry, and the Human Frontier Science Program. She was the director of the Erasysbio-funded Salmonella Host Interactions Project European Consortium (www.shiprec.org) and was the founding co-director of the NSF-funded Center for Biological Language Modeling (www.cs.cmu.edu/~blmt) and the Data Integration and Bioinformatics Core Director of the NIH funded Pittsburgh Centre for HIV Protein Interactions (www.hivppi.pitt.edu). She obtained her PhD with late Nobel Laureate Har Gobind Khorana at the Massachusetts Institute of Technology in Cambridge, USA on conformational changes and folding in rhodopsin. She holds dual undergraduate degrees in Biology and in Chemistry from the University of Cologne, Germany. She has published over 100 papers and has received a number of awards, including the Margaret Oakley Dayhoff Award of the Biophysical Society for the "most promising young woman in biophysics" awarded for her "remarkable work in computational biology embracing the full spectrum of experimental biophysics" in 2007/2008.

Research Projects

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Publications

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Post Graduate Supervision

  • Biophysical studies of membrane protein structure and dynamics Date of Completion:2014-current
  • Identification of biomarkers of weight loss Date of Completion:2015-current

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