Warwick Medical School

WMS

Dr Harpal Randeva

Harpal S Randeva

TITLE   


Senior Lecturer in Endocrinology & Diabetes

Molecular Endocrinology Research Group Head

CONTACT   


Metabolic & Vascular Health
Room B-166
Medical School
Univeristy of Warwick
Gibbet Hill Road
Coventry
CV4 7AL
Tel: 024 7657 2552
Fax: 024 7657 4637
Email: Harpal.Randeva@warwick.ac.uk
Web Link

 


RESEARCH PROFILE


  • Energy homeostasis and metabolism
  • Adrenal and cardiovascular endocrinology
  • Molecular biology of orexins and their receptors
  • Reproductive endocrinology and polycystic ovary syndrome in collaboration with Dr Bee K Tan (Clinical Lecturer)
Dr Randeva leads a team of
  • 1 Non-Clinical Lecturer-Dr Alex Conner is a Non-clinical Lecturer who works in Dr Randeva's group with research interests in GPCR receptor biology and pharmacology. Dr Conner is closely working with Dr Randeva in GPCR research and mutational analysis of receptors. His work also includes neuropsychopharmacology and the genetics of psychiatric disease.
  • 1 Senior Research Fellow-Dr Jing Chen is a Senior Research Fellow, in Dr Randeva's team, works on Orexin and Adiponectin receptor biology.
  • 3 Post Doctoral Fellows-Dr Vanlata Patel and Dr Raghu Adya are working on cardiovascular endocrinology. Dr Patel works on exvivo cardiovascular physiology, studying the effects of adipokines on both isolated Langendorff and the working heart systems. Dr Adya is a newly appointed Research Fellow who is working on endothelial angiogenesis and inflammation. His work also includes the wire-myograph system to measure effect of adipkines on vascular reactivity. Dr Manjunath Ramanjaneya is a Wellcome Trust VIP fellow. His research interests includes adipose tissue biology and the effects of adipokines on adrenal function.


RESEARCH GROUPS



CURRENT RESEARCH PROJECTS


  • Supplement to "Orexin Receptors in the Heart-Electrophysiological Characterisation" (£18,500 for equipment), Funded by: General Charities of the City of Coventry, Project Start Date: 20/01/2011 Project End Date: 30/06/2013
  • The Role of Metabolic Related Molecules in Prostate Cancer, Funded by: University Hospitals Coventry and Warwickshire NHS Trust, Project Start Date: 19/12/2011 Project End Date: 30/09/2012
  • Agreement for supply of free drug, Increlex, Funded by: IPSEN Limited, Project Start Date: 16/08/2009 Project End Date: 15/08/2012
  • Role of recombinant human IGF1 in cardiovascular disease, with Dr Vanlata H Patel - Clinical Sciences Research Institute, Funded by: IPSEN Limited, Project Start Date: 07/07/2011 Project End Date: 17/04/2012

    View all Research Projects


SELECTED PUBLICATIONS


  • Lewandowski K, Nadel I, Lewinski A, Bienkiewicz M, Tan B, Randeva HS, Cypryk K. (2011) 'Positive correlation between serum omentin and thrombospondin-1 in gestational diabetes despite lack of correlation with insulin resistance indices. ' Ginekologia Polska 81 (12), 907 - 912 (0017-0011) [article]
  • Tan BK, Hallschmid M, Adya R, Kern W, Lehnert H, Randeva HS(2011) 'Fibroblast Growth Factor 21 (FGF21) in Human Cerebrospinal Fluid: Relationship With Plasma FGF21 and Body Adiposity. ' Diabetes 60 (11), 2758 - 2762 (0012-1797) [article]
  • Tan BK, Adya R, Randeva HS. (2011) 'Omentin: a novel link between inflammation, diabesity, and cardiovascular disease. ' Trends in Cardiovascular Medicine 20 (5), 143 - 148 (1050-1738) [article]
  • Ramanjaneya M, Conner AC, Brown JE, Chen J, Digby JE, Barber TM, Lehnert H, Randeva HS. (2011) 'Adiponectin (15-36) stimulates steroidogenic acute regulatory (StAR) protein expression and cortisol production in human adrenocortical cells: role of AMPK and MAPK kinase pathways. ' Biochimica Et Biophysica Acta - General Subjects 1813 (5), 802 - 809 (0006-3002) [article]
  • Chambers AE, Stanley PF, Randeva H, Banerjee S. (2011) 'Microvesicle-mediated release of soluble LH/hCG receptor (LHCGR) from transfected cells and placenta explants. ' Reproductive Biology and Endocrinology 15 (9), 64 (1477-7827) [article]

View all Publications

Conferences


Update My Profile on the Warwick eRA Portal My Profile last updated: 05/12/2011

 

Page contact: Hannah Poulton Last revised: Wed 23 Dec 2009
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