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Prof David Spanswick

Job Title
Professor of Molecular Neurosciences
Department
WMS - Biomedical Sciences
Phone
024 765 74868
Web Link
Research Interests

Main areas of research interests are broadly three-fold and relate to: Neuronal electrical synapses in health and disease. Central autonomic control of organ, body and cardiovascular homeostasis in health and disease at the level of the hypothalamus. These interests are related in that electrotonic coupling is an important feature of autonomic sympathetic preganglionic neurones (SPN) and the SPN are the model for health and disease that research within the group has previously focused on. Future research aims are to build upon and develop already on-going projects relating to these general themes. The work involves combined electrophysiological, anatomical and molecular approaches in collaboration with colleagues both overseas and within the UK.

  • Lee, Kevin, Spanswick, David, 2006. Pain - Introduction. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, pp. 541-543
Title Funder Award start Award end
MRC iCASE Agreement NeuroSolutions Ltd NeuroSolutions Limited 01 Oct 2018 30 Sep 2022
Extension to RMRMV0050 An Investigation of the Intrinsic Electrophysiological Properties of Hypothlamic and Spinal Neurone NeuroSolutions Limited 01 Dec 2012 31 Dec 2014
Warwick Systems Biology Doctoral Training Centre EPSRC 01 Oct 2006 01 Oct 2013
The functional role of 5-HT and MC4 receptors in the central regulation of appetite: a combined neurophysiological and molecular approach University of Lubeck 01 Jan 2009 03 Jun 2011
An Investigation of the Intrinsic Electrophysiological Properties of hypothalamic and spinal neurones and their utility as markers of neurol function NeuroSolutions Limited 01 Apr 2009 31 Dec 2010
CASE - Intrinsic Primary Afferent Neurones of the Human and Guinea Pig Enteric Nervous Systems: Basic Neurophysiology and Effects of Prokinetic Peptides Sukhdav Vairea GlaxoSmithKline Research and Development Ltd 01 Oct 2005 30 Sep 2008
Adiponectin as a Peripheral and central Metabolic Adipocytokine in Regulating Energy Homeostasis Dysregulated by Obesity and Diabetes Medical Research Fund of Warwick 01 Nov 2005 31 Oct 2007
Integration of signalling mechanisms in NPY/Agouti related protein (NPY/AgRP) pacemaker neurons in the arcuate nucleus of the hypothalamus BBSRC 01 Oct 2004 30 Sep 2007
CASE STUDENTSHIP: Louise Saker NeuroSolutions Limited 01 Oct 2004 30 Sep 2007
Modulation of neuronal activity patterning by electrotonic coupling in the amygdala Wellcome Trust 01 Apr 2004 31 Mar 2007
Molecular Characterisation of Gap Juntions expressed by electrotonically coupled sympathetic preganglionic neurones. BBSRC 15 Feb 2006 31 Aug 2006
Understanding the Action of Ghrelin in the Brain: Identification of Novel Treatments for hyperghrelinaemia The Prader-Willi Syndrome Association (USA) 01 Dec 2004 30 Nov 2005
Understanding the action of ghrelin in the brain: Identification of novel treatments for hyperghrelinaemia The Prader-Willi Syndrome Association (USA) 01 Oct 2003 31 Aug 2005
Understanding the action of ghrelin in the brain: Identification of novel treatments for hyperghrelinaemia The Prader-Willi Syndrome Association (USA) 01 Oct 2003 30 Jun 2004