Lewandowski group in collaboration with Grzesiek (Basel, Switzerland) and Samoson (Tallinn, Estonia) groups have introduced a new solid-state NMR based approach that enables quantitative structural and dynamics studies of large protein complexes in a few nanomole quantities. The method is demonstrated on a >300 kDa protein-antibody complex. This manuscript signifying a dawn of new era for high resolution NMR studies of large protein complexes has been featured in JACS Spotlights. Read the article in JACS.