Chemistry

Chemistry

Dr. Ann Dixon

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Dr. Ann M. Dixon
Associate Professor of Biological Chemistry
 

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Research Summary
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Developing methods for describing the assembly, interactions and three-dimensional structures of membrane proteins using biophysical and computational techniques, including NMR spectroscopy. Of particular interest are membrane proteins associated with virally-induced cancers, which have demonstrated membrane protein-mediated mechanisms of cellular transformation.

Selected Publications
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Helical Membrane Peptides to Modulate Cell Function
Beevers, A. and Dixon, A.M., Chemical Society Reviews, 2010, 39, 2146-2157.
 
Sequence Dependent Oligomerization of the Neu Transmembrane Domain Suggests Inhibition of ‛Conformational Switching’ by Oncogenic Mutant
Beevers, A., Damianoglou, A., Oates, J., Rodger, A., Dixon, A.M., Biochemistry, 2010, 49, 2811-2820.
 
Evidence for Role of Transmembrane Helix-Helix Interactions in the Assembly of the Class II Major Histocompatibility Complex
King, G. and Dixon, A.M., Molecular BioSystems, 2010, 6, 1650-1661.
 
Towards a structural understanding of the smallest known oncoprotein: Investigation of the bovine papillomavirus E5 protein using solution-state NMR
King, G., Oates, J., Patel, D., van den Berg, H.A., Dixon, AM., Biochimica et Biophysica Acta - Biomembranes, DOI: 10.1016/j.bbamem.2010.11.004.
 
 

Page contact: Giovanni Costantini Last revised: Tue 29 Mar 2011
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