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    Department of Chemistry

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    • David Fox »
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    University of Warwick

    Dr David Fox

    Dr David J. Fox
    Lecturer and EPSRC Advanced Research Fellow

    B.A. D.Phil.

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    Research Summary
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    1) Medicinal chemistry - drug discovery, such as clinical candidate FX125L for inflammatory diseases such as for asthma and related conditions, and the development of mechanistic probes for the discovery of new biological mechanisms.

    2) Reaction mechanism of asymmetric and catalytic processes using kinetics and DFT modelling - organolithium reactions, transition metal catalysed reactions and organocatalysis.
    Selected Publications
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    Mechanism of Catalytic Cyclohydroamination by Zirconium Salicyloxazoline Complexes
    L. E. N. Allan, G. J. Clarkson, D. J. Fox, A. L. Gott, and P. Scott, '' J. Am. Chem. Soc., 2010, 132, 15308–15320. DOI: 10.1021/ja106588m

    Highly potent, orally-available anti-inflammatory broad-spectrum chemokine inhibitors.
    D.J. Fox, J. Reckless, H. Lingard, S. Warren and D.J. Grainger, ’ J. Med. Chem. 2009, 52, 3591–3595.

    The lithiation and acyl transfer reactions of phosphine oxides, sulfides and boranes in the synthesis of cyclopropanes.
    C. Clarke, D.J. Fox, D. Sejer Pedersen and S. Warren Org. Biomol. Chem. 2009, 7, 1329 - 1336.

    An Investigation into the Tether Length and Substitution Pattern of Arene-Substituted Complexes for Asymmetric Transfer Hydrogenation of Ketones. F.K. Cheung, C. Lin, F. Minissi, A. Lorente, M.A. Graham, D.J. Fox and M. Wills, Org. Lett., 2007, 9, 4659-4662.


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    General Enquiries:
    • Telephone: +44 (0)24 76 523653
    • Fax: +44 (0)2476 524112
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    • Undergraduates: +44 (0)2476 523678
    • Master AS:MIT: +44 (0)2476 572970
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    Department of Chemistry, University of Warwick, Gibbet Hill, Coventry, CV4 7AL

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    Page contact: Giovanni Costantini Last revised: Wed 2 Mar 2011
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