Nationality: British Citizen

Qualifications: The University of Warwick: Chemistry MChem (Hons), IAMBEC MSc (Distinction)

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Research Interests

• Synthesis of Protein-Polymer Conjugates via Grafting From and To Approaches
• Characterisation of Protein-Polymer Conjugates via Different Analytical Techniques including high field NMR studies
• Application of Thio-ene 'Click' Chemistry to Functionalise Polymers
• Application of Chromatography to Seperate and Quantify Polymers in Complex Mixtures

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Selected publications

Antibacterial Effects of Poly(2-(dimethylamino ethyl)methacrylate) against Selected Gram-Positive and Gram-Negative Bacteria

Lee-Anne B. Rawlinson, Sinead M. Ryan, Giuseppe Mantovani, Jay A. Syrett, David M. Haddleton and David J. Brayden. Biomacromolecules 2010, 11 (2), pp 443–453

Glycopolymers via catalytic chain transfer polymerisation (CCTP), Huisgens cycloaddition and thiol-ene double click reactions,

L. Nurmi, J. Lindqvist, R. K. Randev, J. Syrett and D. M. Haddleton, Chemical Communications, 2009, 2727-2729

Site-specific N-terminus conjugation of poly(mPEG(1100)) methacrylates to salmon calcitonin: synthesis and preliminary biological evaluation,

C. T. Sayers, G. Mantovani, S. M. Ryan, R. K. Randev, O. Keiper, O. I. Leszczyszyn, C. Blindauer, D. J. Brayden and D. M. Haddleton, Soft Matter, 2009, 5, 3038-3046

Site-Directed Conjugation of "Clicked" Glycopolymers To Form Glycoprotein Mimics: Binding to Mammalian Lectin and Induction of Immunological Function. 

Jin Geng, Giuseppe Mantovani, Lei Tao, Julien Nicolas, Gaojian Chen, Russell Wallis, Daniel A. Mitchell, Benjamin R. G. Johnson, Stephen D. Evans, and David M. Haddleton. Journal of the American Chemical Society (2007), 129(49), 15156-15163.

Fluorescently tagged polymer bioconjugates from protein derived macroinitiators. 

Nicolas, Julien; San Miguel, Veronica; Mantovani, Giuseppe; Haddleton, David M, Chemical Communications, 2006, 45, 4697-4699

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