Research Summary

New methods of polymer synthesis and catalysis. Specific interests include controlled polymerisation of acrylics and esters by organometallic initiators and catalysts, e.g. atom transfer living polymerisation, catalytic chain transfer polymerisation. Mechanisms of polymerisation and utilisation of this knowledge to design catalysts and organic polymers for specific commercial applications. Environmentally friendly polymerisation and use of biomimetic chemistry in this area.

Selected Publications

• Phosphine-mediated one-pot thiol-ene "click'' approach to polymer-protein conjugates
  M. W. Jones, G.  Mantovani, S. M. Ryan, X. X. Wang, D. J. Brayden, D. M. Haddleton, Chemical Communications  2009, 35, 5272-5274

• Glycopolymers via catalytic chain transfer polymerisation (CCTP), Huisgens cycloaddition and thiol-ene double click reactions, L. Nurmi, J. Lindqvist, R. Randev, J. Syrett and D. M. Haddleton, Chemical Communications  2009, 19, 2727-2729

• Advances in PEGylation of important biotech molecules: delivery aspects, S. M. Ryan, G. Mantovani, X. X. Wang, Haddleton, D. M. And D. J. Brayden, Expert Opinion on Drug Delivery, 2008, 5, 371-383

• Polymerization of Methyl Acrylate Mediated by Copper(0)/Me-6-TREN in Hydrophobic Media Enhanced by Phenols; Single Electron Transfer-Living Radical Polymerization, P. M. Wright, G.  Mantovani, D. M. Haddleton, Journal of Polymer Science Part A- Polymer Chemistry, 2008, 46, 7376-7385