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    Department of Chemistry

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    University of Warwick

    Prof. Peter O'Connor

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    Prof. Peter O'Connor
    Professor of Analytical Chemistry

    Ph.D. Cornell University, Ithaca, NY, USA

    B.Sc. University of North Texas, Denton, Tx, USA

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    Research Summary
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    Improving the performance and applications of Fourier Transform Ion Cyclotron Resonance (FTICR) mass spectrometers. We work collaboratively with other research groups to demonstrate the effectiveness of higher specification FTICR mass spectrometry in specific applications. Particular focus in recent years has been on fundamental studies of the mechanism of electron capture dissociation, FTICR instrument design, post-translational modification analysis of proteins and peptides, deamidation and isomerization of aspartic acid residues in peptides and proteins, etc.

    Selected Publications
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    Identification of Aspartic and Isoaspartic Acid Residues in Amyloid beta Peptides, Including A beta 1-42, Using Electron-Ion Reactions
    Sargaeva, N. P.; Lin, C.; O'Connor, P. B., Analytical Chemistry, 2009, 81, 9778-9786.

    Probing the gas-phase folding kinetics of peptide ions by IR activated DR-ECD
    Lin, C.; Cournoyer, J. J.; O'Connor, P. B., Journal of the American Society for Mass Spectrometry, 2008, 19, 780-789.

    Quantitative Determination of Isotope Ratios from Experimental Isotopic Distributions
    Kaur, P.; O'Connor, P. B., Analytical Chemistry 2007, 79, 1198-1204.

    A Detailed Map of Oxidative Post-translational Modifications of Human p21ras using Fourier Transform Mass Spectrometry
    Zhao, C.; Sethuraman, M.; Clavreul, N.; Kaur, P.; Cohen, R. A.; O'Connor, P. B., Analytical Chemistry 2006, 78, 5134-5142.
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    General Enquiries:
    • Telephone: +44 (0)24 76 523653
    • Fax: +44 (0)2476 524112
    Admissions:
    • Undergraduates: +44 (0)2476 523678
    • Master AS:MIT: +44 (0)2476 572970
    • Graduate PhD enrolment: +44 (0)2476 522230
    Address

    Department of Chemistry, University of Warwick, Gibbet Hill, Coventry, CV4 7AL

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    Page contact: Giovanni Costantini Last revised: Mon 19 Sep 2011
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