Chemistry

Chemistry

Prof. Peter O'Connor

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Prof. Peter O'Connor
Professor of Analytical Chemistry

Ph.D. Cornell University, Ithaca, NY, USA

B.Sc. University of North Texas, Denton, Tx, USA

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Research Summary
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Improving the performance and applications of Fourier Transform Ion Cyclotron Resonance (FTICR) mass spectrometers. We work collaboratively with other research groups to demonstrate the effectiveness of higher specification FTICR mass spectrometry in specific applications. Particular focus in recent years has been on fundamental studies of the mechanism of electron capture dissociation, FTICR instrument design, post-translational modification analysis of proteins and peptides, deamidation and isomerization of aspartic acid residues in peptides and proteins, etc.

Selected Publications
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Probing the gas-phase folding kinetics of peptide ions by IR activated DR-ECD
Lin, C.; Cournoyer, J. J.; O'Connor, P. B., Journal of the American Society for Mass Spectrometry, 2008, 19, 780-789.

Quantitative Determination of Isotope Ratios from Experimental Isotopic Distributions
Kaur, P.; O'Connor, P. B., Analytical Chemistry 2007, 79, 1198-1204.

A Detailed Map of Oxidative Post-translational Modifications of Human p21ras using Fourier Transform Mass Spectrometry
Zhao, C.; Sethuraman, M.; Clavreul, N.; Kaur, P.; Cohen, R. A.; O'Connor, P. B., Analytical Chemistry 2006, 78, 5134-5142.
Page contact: Giovanni Costantini Last revised: Mon 19 Sep 2011
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