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New TB drug candidates developed from soil bacteria
A new treatment for tuberculosis (TB) is set to be developed using compounds derived from bacteria that live in soil - according to an international collaboration of researchers, including the University of Warwick.
The research, ‘Sansanmycin Natural Product Analogues as Potent and Selective Anti-Mycobacterials that Inhibit Lipid I Biosynthesis’ is published in Nature Communications today.
The collaboration was led by the University of Sydney, and included the University of Warwick, Monash University, Colorado State University, Simon Fraser University, and the University of Queensland.
Key reagents and expertise in antimicrobial resistance from the research groups of Dr David Roper, Professor Chris Dowson and Professor Tim Bugg at the University of Warwick, played a crucial role in successfully targeting TB bacteria with the new compounds.
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