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    School of Life Sciences

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    • Prof. Andrew Easton
    University of Warwick

    Prof. Andrew Easton

    Andrew Easton

    CONTACT   


    Life Sciences
    University of Warwick
    Coventry
    CV4 7AL
    Tel: 76523517
    Fax: 02476523568
    Email: A.J.Easton@warwick.ac.uk
    Pneumovirus Research Laboratory

     


    RESEARCH PROFILE


    Research in the laboratory focuses on the molecular biology of viruses which use a single stranded negative sense RNA molecule as genome. Of particular interest are paramyxoviruses which are responsible acute respiratory infections in their host, though other negative strand viruses are studied for comparison. We have worked for many years on various aspects of the molecular biology of pneumoviruses, which include respiratory syncytial virus, pneumonia virus of mice and avian pneumovirus. Much of our work uses the technique of reverse genetics for analysis of important regulatory sequences controlling virus RNA synthesis and identification of functional domains in proteins involved in virus RNA synthesis. Recently, we have begun work on the protective capacity of specific genome deletions of influenza virus in collaboration with Professor Nigel Dimmock. More details on these viruses and our research interests are available on the Pneumovirus Laboratory website .


    RESEARCH GROUPS


    • Infectious Agents

    BACKGROUND


    BSc (Biochemistry) University of Aberdeen

    PhD (Virology) University of Glasgow


    CURRENT RESEARCH PROJECTS


    • Translation Award: FluPro - a novel flu antiviral, with Professor Nigel J Dimmock, Biological Sciences, - - - Professor Andrew J J Easton - Biological Sciences Dr Anthony C. C Marriott - Biological Sciences, Funded by: Wellcome Trust, Project Start Date: 01/05/2010 Project End Date: 30/04/2015
    • Phd Studentship ? Optimisation of current diagnostic capabilities and restrictions to vaccine efficacy for the Lyssaviriuses Students Name: Jenni Evans , Funded by: Animal Health and Veterinary Laboratories Agency, Project Start Date: 01/11/2011 Project End Date: 30/09/2014
    • The Development of Novel Multivalent Vaccines, Funded by: BBSRC, Project Start Date: 01/03/2010 Project End Date: 28/02/2014
    • Analysis of the mechanism for coupled transition in cellular virus mRNAs, with - - Dr Sascha Ott - Systems Biology Centre, Funded by: BBSRC, Project Start Date: 01/03/2011 Project End Date: 28/02/2014

      View all Research Projects


    SELECTED PUBLICATIONS


    • Scott, P.D., et al.(2011) 'Defective interfering influenza virus confers only short-lived protection against influenza virus disease : evidence for a role for adaptive immunity in DI virus-mediated protection in vivo' Vaccine 29 (38), 6584 - 6591 (0264-410X) [article]
    • Scott Paul D.; Meng Bo; Marriott Anthony C.; et al.(2011) 'Defective interfering influenza A virus protects in vivo against disease caused by a heterologous influenza B virus' Journal Of General Virology 92 2122 - 2132 (0022-1317)
    • Smith, C. M., et al.(2011) 'Cooling of cilia allows functional analysis of the beat pattern for diagnostic testing' Chest 140 (1), 186 - 190 (0012-3692) [article]
    • Scott Paul D.; Meng Bo; Marriott Anthony C.; et al.(2011) 'Defective interfering virus protects elderly mice from influenza' Virology Journal 8 (1743-422X)
    • Easton, A.J., et al.(2011) 'A novel broad-spectrum treatment for respiratory virus infections : influenza-based defective interfering virus provides protection against pneumovirus infection in vivo' Vaccine 29 (15), 2777 - 2784 (0264-410X) [article]

    View all Publications


    Update My Profile on the Warwick eRA Portal My Profile last updated: 01/05/2012

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    School of Life Sciences, Gibbet Hill Campus, The University of Warwick, Coventry, CV4 7AL
    Email: life dot sciences at warwick dot ac dot uk Tel: +44 (0)24 765 74251 Fax: +44 (0)24 765 23568
    Warwick Crop Centre is located on our Wellesbourne campus.

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