Dr Isabelle Carre

Isabelle Carre

CONTACT   

Life Sciences
Room B118
University of Warwick
Coventry
CV4 7AL 		Tel: 02476523544
Fax: 02476523701
Email: Isabelle.Carre@warwick.ac.uk
Circadian clocks in plants

 

RESEARCH PROFILE


My current work aims to (i) investigate and model the function of gene networks underlying circadian oscillators and photoperiodic flowering, and (ii) decipher the regulatory logic within gene promoters that underlies specific temporal patterns of transcription.

RESEARCH GROUPS

BACKGROUND


As part of my PhD degree at Stony Brook University (New York), I demonstrated the role of cyclic AMP in the circadian control of cell division in Euglena, a unicellular alga. Frustrated by the lack of genetics in this system, I chose during my post-doctoral training to work on Arabidopsis thaliana, then an emerging system for plant molecular genetics. As part of the NSF centre for Biological Timing at The University of Virginia, I studied the control of rhythmic transcription by the plant circadian clock. In 1996 I took up an independent position as a Warwick Research Fellow. My early work investigated the role of the circadian clock in the seasonal control of flowering, and led to the identification of some of the key components of the clock mechanism. This led to a lectureship in 2002 and an associate professorship in 2005.

CURRENT RESEARCH PROJECTS


  • Global control of rythmic gene expression by transcription factor LHY, with Ott, Sascha~Finkenstadt, Barbel F, Systems Biology Centre~Statistics, Funded by: BBSRC, Project Start Date: 01/06/2008 Project End Date: 31/05/2012

    View all Research Projects

SELECTED PUBLICATIONS


  • Adams, S. and Carre, I. A.(2011) 'Downstream of the plant circadian clock : output pathways for the control of physiology and development' Essays In Biochemistry 49 53 - 69 (0071-1365) [article]
  • Picot, E., Krusche, P., Tiskin, A., Carré, I. and Ott, S.(2010) 'Evolutionary analysis of regulatory sequences (EARS) in plants' Plant Journal, The 64 (1), 165 - 176 (0960-7412) [article]
  • Salazar, J. D., Saithong, T., Brown, P. E., Foreman, J., Locke, J. C. W., Halliday K. J., Carre, I. A., Rand, D. A. and Millar, A. J.(2009) 'Prediction of photoperiodic regulators from quantitative gene circuit models' Cell 139 (6), 1170 - 1179 (0092-8674) [article]
  • Spensley, M., Kim, J. -Y., Picot, E., Reid, J., Ott, S., Helliwell, C. and Carré, I. A.(2009) 'Evolutionarily conserved regulatory motifs in the promoter of the Arabidopsis clock gene LATE ELONGATED HYPOCOTYL' The Plant Cell 21 (9), 2606 - 2623 (1040-4651) [article]
  • Pouteau, S., Carré, I., Gaudin, V., Ferret, V., Lefebvre, D. and Wilson, M.(2008) 'Diversification of photoperiodic response patterns in a collection of early-flowering mutants of arabidopsis' Plant Physiology 148 (3), 1465 - 1473 (0032-0889) [article]

View all Publications

Update My Profile on the Warwick eRA Portal My Profile last updated: 01/03/2012