RESEARCH PROFILE

During my Ph.D I focused on studying the energetic and structural aspects of protein phosphorylation. I investigated the effect of resulting charge-charge interactions of phosphorylation to protein structure and to protein-protein cooperativity, using continuum electrostatics and bioinformatics methods.

I moved from structural biology to paleogenomics after joining the Allaby Research Group.
My current projects involve:
- bioinformatic analysis and evolutionary modelling of ancient DNA obtained from archaeobotanical samples of Nubian barley and new and old world cottons.
- developing stochastic optimisation methods for multiplex PCR primer design.
- developing in silico systems for simulating the early domestication of crops since the Neolithic Era.

BACKGROUND

SELECTED PUBLICATIONS

• Kitchen, J., Saunders, R.E. and Warwicker, J.(2008) 'Charge environments around phosphorylation sites in proteins' BMC Structural Biology 8 (1), (1472-6807) [article]

View all Publications