4 x MRC DTG funded studentships based with Warwick Medical School

Application Deadline 30 March 2012

Your PhD project will involve quantitative imaging in one of many exciting research areas across the life and medical sciences. More information on the Warwick imaging community is available on the Warwick-I website. Students will complete an initial 9 month training period before beginning their PhD project.

The research projects below are in competition for funding. The projects with the best applicants will be awarded the funding. The funding is only available to applicants that meet the eligibility criteria.

Click on the 'Warwick-I website' link above to view the PhD projects descriptions.

• Quantitative analysis of the spatial and temporal dynamics regulating G proteins signalling (Supervised by Dr Graham Ladds)
• Exploring ultrafast dynamics of photoactivated anti-cancer complexes (Supervised by Dr Vasilios Stavros and Professor Peter Sadler FRS)
• The effect of glucose and TGF-β on cell-cell interactions in the proximal tubule (Supervised by Dr Paul Squires)
• Role of endosulfines in budding yeast meiosis (Supervised by Dr Prakash Arumugam)
• Quantitative imaging of regulatory proteins in the eukaryotic gene expression pathway (Supervised by Professor John McCarthy)
• Characterising intermolecular interactions that underpin eukaryotic protein synthesis (Supervised by Professor John McCarthy)
• Connexin 26 and the CO2-dependent control of cerebrovascular blood flow (Supervised by Professor Nick Dale and Professor Georgy Koentges)
• Molecular mechanisms of spindle checkpoint silencing (Supervised by Professor Jonathan Millar and Dr Prakash Arumugam)
• Role and regulation of kinesis-8 motor proteins in mitosis (Supervised by Professor Jonathan Millar and Professor Andrew McAinsh)
• Role of mechanical friction and hydrodynamic shear in the cytoadherence to host endothelium of RBCs infected by the malaria parasite, Plasmodium falciparum (Supervised by Professor Robert Cross and Professor Alister Craig)
• Mitotic Motor Systems (Supervised by Dr Andrew McAinsh)
• How can CCAN power chromosome movement? (Supervised by Dr Andrew McAinsh)
• Mass spectrometry-based imaging of biological molecules in tissue samples (Supervised by Professor Jim Scrivens)
• Control of force generation in migrating cells (Supervised by Dr Anne Straube)
• Quantitative study of age-related changes in the neuron-glia interaction (Supervised by Dr Yuriy Pankratov)
• Single molecule mechanics of partially drug-inhibited mitotic molecular motors (Supervised by Dr Nick Carter and Professor Rob Cross)
• Cooperative central spindle microtubule bundling by centralspindlin and PRC1 under mechanical tension (Supervised by Dr Masanori Mishima and Dr Nick Carter)
• Novel insight into Human Brown adipose function and activity, implications for combating Obesity and Type 2 Diabetes (Supervised by Dr Tom Barber, Dr Philip McTernan and Dr Ponnusamy Saravanan)
• A translational approach to developing non-invasive bioimaging of the capillary microcirculation into a biomarker for patients at increased risk of clinical vascular disease (Supervised by Professor Donald Singer, Professor Robert Kerr and Dr Eliak Somfai)
• Mechanisms regulating meiotic chromosome segregation during budding yeast meiosis (Supervised by Dr Prakash Arumugam and Professor Jonathan Millar)
• Defining the role of uterine gap junction protein B2 (Connexin 26) expression in embryo implantation, pregnancy and labour (Supervised by Professor Nick Dale, Dr Andrew Blanks and Professor Jan Brosens)
• Mechanism of EB2 modulating microtubule structure (Supervised by Dr Anne Straube and Dr Corrine Smith)
• Single molecule imaging of clathrin cage assemblies (Supervised by Dr Corrine Smith and Dr Nick Carter)

Eligibility

In brief, candidates are required to satisfy two principal eligibility conditions (Residence and Qualification)

Residence

• British nationals who have lived in the UK all their lives are eligible.
• Also eligible are non-British nationals who have settled status AND have been resident in the UK for 3 years immediately prior to the date of the start of the course.
• EU nationals who have been ordinarily resident in the UK and Islands for three years immediately prior to the date of start of the course;
• EU nationals not resident in the UK are eligible for a fees-only award. In the event of receiving such an award, you would have to make separate arrangements to defray the costs of accommodation and subsistence.
• EEA and Swiss nationals (EEA migrant workers) should refer to the full guidelines to check eligibility

Academic requirement

• Those who have a 1st or a 2.1 undergraduate degree in a relevant field are eligible.
• Those who have a 2.2 and an additional Masters degree in a relevant field may be eligible.
• Those who have a 2.2 and at least three years post-graduate experience in a relevant field may be eligible.
• Those with degrees abroad (as well as, perhaps, postgraduate experience) may be eligible if their qualifications are deemed equivalent to any of the above

Full eligibility can be viewed on the MRC website.