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    Molecular Organisation and Assembly in Cells

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    University of Warwick

    Paul Harrison

    Background

    I finished my masters in mathematics in 2008, where I attained Upper Second Class honours. After the broad curriculum of the first half of my degree, my third and fourth years took a narrower focus where I specialised in various fields of applied mathematics such as mathematical biology, fluid mechanics, and theoretical physics. I went on to spend the next two years on an industrial graduate training scheme where my research was a combination of materials physics and electronics theory. I made extensive use of finite element methods to model the propagation of high pressure shock waves in piezoelectric materials instigated by high velocity impacts. I then used various numerical methods to solve the corresponding circuit and predict the electrical output of the system.

    In 2010, after finishing my graduate training scheme, I decided to change fields and pursue a career in life sciences. I wanted to keep a large mathematical component to my research so I joined MOAC in October 2010, completing a MSc in Mathematical Biology and Biophysical Chemistry the following September. Over the course of that year I settled on neuroscience as my field of choice, in which I am currently studying for a PhD.

    Previous Education

    University of Warwick
    September 2010 - September 2011: MSc with distinction in Mathematical Biology and Biophysical Chemistry
    Oriel College, University of Oxford
    September 2004 - May 2008: MMath Upper Second Class (Hons) in Mathematics

    PhD: Experimentally Verified Models of the Neocortical Microcircuit

    neuron.jpg

    The neocortex is the most evolutionary recent part of the brain located in the outer cerebral hemispheres and is responsible for high level functioning such as motor control and conscious thought. It is divided into distinct layers characterised by neuronal classification, as well as vertical columns containing their own local circuitry - neocortical microcircuits. My PhD project aims to derive both reduced and spatially extended models of various classes of neocortical neuron and verify them experimentally using whole-cell patch clamp techniques. I then aim to use these in mathematically tractable microcircuit models.

    Supervisors

    Theoretical: Dr Magnus Richardson (Warwick Systems Biology Centre)
    Experimental: Dr Mark Wall (Warwick School of Life Sciences)


    me.jpg

    MOAC DTC
    Coventry House
    University of Warwick
    Coventry
    CV4 7AL

    paul.harrison@warwick.ac.uk

    MOAC DTC, Coventry House, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL
    Tel. 024 765 75808 moac2 at warwick dot ac dot uk

    How to find us

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    Page contact: Paul Harrison Last revised: Fri 18 May 2012
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