Academic background:

The University of Warwick

2008 - present: PhD A Molecular and Systems Analysis of G-protein mediated signalling

2007-2008: MSc Systems Biology (Systems Biology Doctoral Training Centre)

The University of Birmingham

2006-2007 MSc Intelligent Systems Engineering (school of computer science)

2003-2006 BSc Bioinformatics (school of biosciences)

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Current Research

A Molecular and Systems Analysis of G protein-mediated signalling.

The overall aim of this project is to utilise a combination of in vivo experimentation with computational modelling, to produce a mechanistic understanding of the molecules that regulate signalling networks mediated by heterotrimeric G proteins. The pheromone response pathway in Schizosaccharomyces pombe will be used as a model for G protein mediated signalling.We aim to develop an in depth and quantitative understanding of the molecular machinery that enables RGS proteins to set the threshold levels of eukaryotic GPCR signalling. Through a combination of in vivo experimentation and computational modelling it is hoped that a unified quantitative description of eukaryotic GPCR regulation will be generated.

Supervisors:

Dr Graham Ladds

graham.ladds@warwick.ac.uk

Professor David Rand

D.A.Rand@warwick.ac.uk

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CONTACT DETAILS:

w dot d dot croft at warwick dot ac dot uk

 

Lab: M119

Department of Biological Sciences

Gibbet Hill Campus

Gibbet Hill Road

University of Warwick

Coventry, CV47AL