Skip to main content Skip to navigation

Articles

Publications which have received peer review. Student co-authors indicated in bold.

DJ Diehl, MS Keshavan, E Kanal, RD Nebes, TE Nichols, and JS Gillen. Post-ECT increases in MRI regional T2 relaxation times and their relationship to cog-nitive side effects: a pilot study. Psychiatry Research, 54(2):177–84, November, 1994.

DJ Diehl, MA Mintun, RY Moore, TE Nichols, and DJ Kupfer. Diurnal variation in baseline human regional cerebral blood flow demonstrated by positron emission tomography: Preliminary findings. Psychiatry Research: Neuroimaging, 1995.

SB Baumann, DC Noll, DS Kondziolka, W Schneider, TE Nichols, MA Mintun, JD Lewine, H Yonas, WW Orrison, and RJ Sclabassi. Comparison of functional magnetic resonance imaging with positron emission tomography and magnetoen-cephalography to identify the motor cortex in a patient with an arteriovenous mal-formation. Journal of Image Guided Surgery, 1(4):191–197, 1995.

JT Becker, MA Mintun, K Aleva, MB Wiseman, T Nichols, and ST Dekosky. Alterations in functional neuroanatomical connectivity in alzheimer’s disease. positron emission tomography of auditory verbal short-term memory. Annals of the New York Academy of Sciences, 777:239–242, January 1996.

JJ Mann, KM Malone, DJ Diehl, J Perel, TB Cooper, and MA Mintun. Demonstration in vivo of reduced serotonin responsivity in the brain of untreated depressed patients. American Journal of Psychiatry, 153(2):174–182, February 1996.

JT Becker, MA Mintun, K Aleva, MB Wiseman, T Nichols, and ST DeKosky. Compensatory reallocation of brain resources supporting verbal episodic memory in alzheimer’s disease. Neurology, 46(3):692–700, Mar 1996.

AN Herbster, TE Nichols, MB Wiseman, MA Mintun, ST DeKosky, and JT Becker. Functional connectivity in auditory-verbal short-term memory in alzheimer’s dis-ease. NeuroImage, 4(2):67–77, October 1996.

JJ Mann, KM Malone, DJ Diehl, J Perel, TE Nichols, and MA. Mintun. Positron emission tomographic imaging of serotonin activation effects on prefrontal cortex in healthy volunteers. Journal of Cerebral Blood Flow & Metabolism, 16(3):418–26, May 1996.

CS Carter, MA Mintun, TE Nichols, and JD Cohen. Anterior cingulate gyrus dysfunction and selective attentional dysfunction in schizophrenia: An [15 O]-H2 O PET study during b stroop task performance. American Journal of Psychiatry, 154(12):1670–1675, December 1997.

R Ganguli, C Carter, M Mintun, J Brar, J Becker, R Sarma, T Nichols, and E Ben-nington. PET brain mapping study of auditory verbal supraspan memory versus visual fixation in schizophrenia. Biological Psychiatry, 41(1):33–42, January 1997.

GS Smith, JC Price, BJ Lopresti, Y Huang, N Simpson, D Holt, NS Mason, CC Meltzer, R Sweet, T Nichols, D Sashin, and C Mathis. Test-retest variability of positron emission tomography (PET) and [18F]-altanserin for the in vivo imaging of serotonin (5-HT2A) receptors in the human brain. Synapse, 30:380–392, 1998.

AP Holmes, JD Watson, and TE Nichols. Holmes and Watson on ‘Sherlock’. Journal of Cerebral Blood Flow & Metabolism, 18(6):697–8, June 1998. Comment on

Performance of a randomization test for single-subject (15)O-water PET activation studies, M Halber, K Herholz, K Wienhard, G Pawlik, WD Heiss, JCBFM 17:1033-9.

EA Nofzinger, TE Nichols, DJ Kupfer, and RY Moore. Changes in forebrain function from waking to REM sleep in depression: Preliminary analyses of [18F]-FDG PET studies. Psychiatry Research: Neuroimaging, 91(2):59–78, August 1999.

TE Nichols, J Qi, and RL Leahy. Continuous time dynamic PET imaging using list mode data. In Information Processing in Medical Imaging, volume 1613 of Lecture Notes in Computer Science, pp 98–111, Berlin, 1999. Springer-Verlag. Proceedings of the 16th International Conference, IPMI’99.

KM Petersson, TE Nichols, J-B Poline, and AP Holmes. Statistical limitations in functional neuroimaging II. Signal detection and statistical inference. Philosophical Transactions of the Royal Society: Biological Sciences, 354:1261–1281, 1999.

KM Petersson, TE Nichols, J-B Poline, and AP Holmes. Statistical limitations in functional neuroimaging I. Non-inferential methods and statistical models. Philosophical Transactions of the Royal Society: Biological Sciences, 354:1239–1260, 1999.

CC Meltzer, PE Kinahan, PJ Greer, TE Nichols, C Comtat, MN Cantwell, and JC Price. Comparative evaluation of MR-based partial volume correction schemes for PET. Journal of Nuclear Medicine, 40:2053–2065, 1999.

E Asma, TE Nichols, J Qi and RM Leahy. 4D Image Reconstruction from List Mode Data. Proceedings, IEEE Nuclear Science Symposium and Medical Imaging Conference, Lyon, France, 2000.

TE Nichols and AP Holmes. Nonparametric Permutation Tests for Functional Neuroimaging: A Primer with Examples. Human Brain Mapping, 15:1-25, 2002.

CR Genovese, N Lazar and TE Nichols. Thresholding of Statistical Maps in Functional Neuroimaging Using the False Discovery Rate. NeuroImage, 15:870-878, 2002.

TE Nichols, J Qi, E Asma and RL Leahy. Spatiotemporal Reconstruction of List Mode PET Data. IEEE Transactions on Medical Imaging, 21:396–404, 2002.

SWG Derbyshire, TE Nichols, AKP Jones, DW Townsend, and L Firestone. Gender differences in patterns of cerebral activation during equal experience of painful laser stimulation. The Journal of Pain, 3:401–411, 2002.

RL Albin, TE Nichols, KA Frey. Brain Imaging to Assess the Effects of Dopamine Agonists on Progression of Parkinson Disease. Letter to The Editor. Journal of the American Medical Association, 288:311–312, 2002.

A Ossadtchi, VM Brown, AH Khan, SR Cherry, T Nichols, RM Leahy, and DJ Smith. Statistical analysis of multiplex brain gene expression datasets. Neurochemical Research, 27:1113–1121, 2002.

E Asma, TE Nichols, RM Leahy. Temporal Resolution Properties of Dynamic PET Images. In Proc. IEEE Nuclear Science Symposium and Medical Imaging Conference, Norfolk, Virginia, 2002.

CY Sylvester, TD Wager, SC Lacey, L Hernandez, TE Nichols EE Smith and J Jonides Switching attention and resolving interference: fMRI measures of executive functions. Neuropsychologia, 41:357–370, 2003.

KL Phan, SF Taylor, RC Welsh, LR Decker, DC Noll, TE Nichols, JC Britton, I Liberzon. Activation of the Medial Prefrontal Cortex and Extended Amygdala by Individual Ratings of Emotional Arousal: An fMRI Study. Biological Psychiatry, 53:211–215, 2003.

TA Leil, A Ossadtchi, TE Nichols, RM Leahy R.M and DJ Smith. Genes regulated by learning in the hippocampus. Journal of Neuroscience Research, 71(6):763–768, 2003.

TD Wager and TE Nichols. Optimization of Experimental Design in fMRI: A General Framework Using a Genetic Algorithm. NeuroImage, 18:293–309, 2003.

WL Luo and TE Nichols. Diagnosis & Exploration of Massively Univariate Neuroimaging Models. NeuroImage, 19:1014–1032, 2003.

D Pantazis, T Nichols, S Baillet, RM Leahy. Spatiotemporal Localization Of Significant Activation In MEG Using Permutation Tests. In Information Processing in Medical Imaging, volume 2732 of Lecture Notes in Computer Science, pp 512–523, Berlin, 2003. Proceedings of the 18th International Conference, IPMI 2003.

RL Albin, RA Koeppe, NI Bohnen, TE Nichols, P Meyer, K Wernette, S Mi-noshima, MR Kilbourn, FA Frey. Increased ventral striatal monoaminergic innervation in Tourette syndrome. Neurology, 61:310–315, 2003.

TE Nichols and S Hayasaka. Controlling the Familywise Error Rate in Functional Neuroimaging: A Comparative Review. Statistical Methods in Medical Research, 12:419–446, 2003.

S Hayasaka and TE Nichols. Validating cluster size inference: random field and permutation methods. NeuroImage, 20:2343–2356, 2003.

S Hayasaka, KL Phan, I Liberzon, KJ Worsley and TE Nichols. Non-Stationary Cluster Size Inference with Random Field and Permutation Methods NeuroImage, 22:676–687, 2004.

E Asma, TE Nichols, RM Leahy. Temporally Invariant Uniform Spatial Resolution in Dynamic PET. In Proc. IEEE Nuclear Science Symposium and Medical Imaging Conference, Portland, OR, 2003.

S Hayasaka and TE Nichols. Combining voxel intensity and cluster extent with permutation test framework. NeuroImage, 23:54–63, 2004.

D Pantazis, TE Nichols, S Baillet and RM Leahy. A comparison of random field theory and permutation methods for the statistical analysis of MEG data. NeuroImage, 25:3830-394, 2005.

TE Nichols, M Brett, J Andersson, T Wager and J-B Poline. Valid conjunction inference with the minimum statistic. NeuroImage, 25:653–660, 2005.

GR Abecasis, D Ghosh and TE Nichols. Linkage disequilibrium: ancient history drives the new genetics. Human Heredity, 59:118–24, 2005

TD Wager, J Jonides, EE Smith, TE Nichols. Toward a taxonomy of attention shifting: individual differences in fMRI during multiple shift types. Cognitive, Affective & Behavioral Neuroscience, 5:127-43, 2005.

J-K Zubieta, JA Bueller, LR Jackson, DJ Scott, Y Xu, RA Koeppe, TE Nichols and CS Stohler. Placebo Effects Mediated by Endogenous Opioid Activity on µ-Opioid Receptors. The Journal of Neuroscience, 25:7754–7762, 2005.

TE Lund, KH Madsen, K Sidaros, W-L Luo and TE Nichols. Non-white noise in fMRI: Does modelling have an impact? NeuroImage, 29:54–66, 2006.

J Mumford & TE Nichols. Modeling & inference of multisubject fMRI data. IEEE Engineering in Medicine and Biology Magazine, 25(2):42–51, 2006.

H Zhang, W-L Luo, TE Nichols. Diagnosis of single-subject and group fMRI data with SPMd Human Brain Mapping, 27:442–451, 2006.

C Enzinger, S Smith, F Fazekas, G Drevin, S Ropele, T Nichols, T Behrens, R Schmidt, PM Matthews Lesion probability maps of white matter hyperintensities in elderly individuals: Results of the Austrian stroke prevention study. Journal of Neurology, 253:1064-1070, 2006

SM Smith, M Jenkinson, H Johansen-Berg, D Rueckert, TE Nichols, CE Mackay, KE Watkins, O Ciccarelli, MZ Cader, PM Matthews and TEJ Behrens. Tract-based spatial statistics: Voxelwise analysis of multi-subject diffusion data NeuroImage, 31:1487–1505, 2006

J-K Zubieta, Y Smith, CS Stohler, TE Nichols, JA Bueller, RA Koeppe. Pro- and Antinociceptive Effects of Estradiol through Endogenous Opioid Neurotransmission in Women. The Journal of Neuroscience, 25(34):7754–7762, 2006

L Hernandez-Garcia, GR Lee, J Mumford, TE Nichols. Estimation Efficiency and Statistical Power in Arterial Spin Labeling fMRI. NeuroImage, 33:103–114, 2006.

A Meyer-Lindenberg, TE Nichols, J Callicot, J Ding, R Straub, B Kolachana, J Buckholtz, VS Mattay, M Egan, DR Weinberger. Impact of complex genetic variation in COMT on human brain function. Molecular Psychiatry, 11(9):867–877, 2006.

YR Smith, T Love, CC Persad, A Tkaczyk, TE Nichols, J-K Zubieta. Hormone Therapy Induced Alterations in Neural Activity: an fMRI Study of Visuospatial Working Memory. Journal of Clinical Endocrinology and Metabolism, 91(11):4476–4481, 2006.

SM Smith, H Johansen-Berg, M Jenkinson, D Rueckert, TE Nichols, KL Miller, MD Robson, DK Jones, JC Klein, AJ Bartsch, TE Behrens. Acquisition and voxelwise analysis of multi-subject diffusion data with tract-based spatial statistics. Nature Protocals, 2(3):499-503, 2007.

C Rorden, L Bonilha, TE Nichols. Rank-order versus mean based statistics for neuroimaging. NeuroImage, 35(4):1531-1537, 2007.

Cameron OG, Huang GC, Nichols T, Koeppe RA, Minoshima S, Rose D, Frey KA. Reduced gamma-aminobutyric Acid(A)-benzodiazepine binding sites in insular cortex of individuals with panic disorder Archives of General Psychiatry, 64(7):793-800, 2007.

RA Poldrack, PC Fletcher, RN Henson, KJ Worsley, M Brett, TE Nichols. Guidelines for reporting an fMRI study. NeuroImage, 40(2):409-414, 2007.

JA Mumford, TE Nichols. Power calculation for group fMRI studies accounting for arbitrary design and temporal autocorrelation. NeuroImage, 39(1):261-268, 2008.

CS Carter, S Heckers, T Nichols, DS Pine, S Strother. Optimizing the Design and Analysis of Clinical FMRI Research Studies. Biological Psychiatry, 64(10):842–849, 2008.

S Purkayastha, TD Wager, and TE Nichols. Inferring individual differences in fMRI: Finding brain regions with significant within subject correlation. Statistica Sinica, 18(4):1483–1500, 2008.

H Zhang and TE Nichols and TD Johnson. Cluster mass inference via random field theory. NeuroImage, 44(1):51–61, 2009.

SM Smith and TE Nichols. Threshold-free cluster enhancement: Addressing problems of smoothing, threshold dependence and localisation in cluster inference. NeuroImage, 44(1):83–98, 2009.

D Pantazis, GV Simpson, DL Weber, CL Dale, TE Nichols and RM Leahy A novel ANCOVA design for analysis of MEG data with application to a visual attention study. NeuroImage, 44(1):164–174, 2009.

N Filippini, A Rao, S Wetten, RA Gibson, M Borrie, D Guzman, A Kertesz, I Loy-English, J Williams, T Nichols, B Whitcher and PM Matthews. Anatomically-distinct genetic associations of APOE ε4 allele load with regional cortical atrophy in Alzheimer’s disease NeuroImage, 44(3):724–728, 2009.

K Bendfeldt, P Kuster, S Traud, H Egger, S Winklhofer, N Mueller-Lenke, Y Naegelin, A Gass, L Kappos, PM Matthews, T Nichols, E-W Radue and SJ Borgwardt. Association of regional gray matter volume loss and progression of white matter lesions in multiple sclerosis – A longitudinal voxel-based morphometry study. NeuroImage, 45(1):60-67, 2009.

RL Albin, RA Koeppe, K Wernette, W Zhuang, TE Nichols, MR Kilbourn, and KA Frey. Striatal [11C]Dihydrotetrabenazine and [11C]Methylphenidate Binding in Tourette Syndrome. Neurology, 72(16):1390–6, 2009.

TD Wager, MA Lindquist, TE Nichols, H Kober, JX Van Snellenberg. Evaluating the consistency and specificity of neuroimaging data using meta-analysis. NeuroImage, 45:S210–S221, 2009.

G Salimi-Khorshidi, SM Smith, JR Keltner, TD Wager, TE Nichols. Metaanalysis of neuroimaging data: A comparison of image-based and coordinate-based pooling of studies. NeuroImage, 45(3):810–823, 2009.

B Inkster, TE Nichols, PG Saemann, DP Auer, F Holsboer, P Muglia, PM Matthews. Association of GSK3beta polymorphisms with brain structural changes in major depressive disorder. Archives of General Psychiatry, 66(7):721–728, 2009.

JA Mumford, T Nichols. Simple group fMRI modeling and inference. Neuroimage, 47(4):1469–1475, 2009.

L Xu, TD Johnson, TE Nichols, DE Nee. Modeling inter-subject variability in fMRI activation location: A Bayesian hierarchical spatial model. Biometrics, 65(4):10410–51, 2009.

K Bendfeldt, H Egger, TE Nichols, P Loetscher, N Denier, P Kuster, S Traud, N Mueller-Lenke, Y Naegelin, A Gass, L Kappos, EW Radue, SJ Borgwardt. Effect of immunomodulatory medication on regional gray matter loss in relapsing-remitting multiple sclerosis–a longitudinal MRI study. Brain Research, 1325:174–82, 2010.

K Bendfeldt, JO Blumhagen, H Egger, P Loetscher, N Denier, P Kuster, S Traud, N Mueller-Lenke, Y Naegelin, A Gass, J Hirsch, L Kappos, TE Nichols, EW Radue, SJ Borgwardt. Spatiotemporal distribution pattern of white matter lesion volumes and their association with regional grey matter volume reductions in relapsing-remitting multiple sclerosis. Human Brain Mapping, in press.

B Inkster, TE Nichols, PG Saemann, DP Auer, F Holsboer, P Muglia, PM Matthews. Pathway-based approaches to imaging genetics association studies: Wnt signaling, GSK3beta substrates and major depression. NeuroImage, in press


Neuroimaging
Statistics

Contact Info

Room D0.03
Deptment of Statistics
University of Warwick
Coventry
CV4 7AL
United Kingdom

Tel: +44(0)24 761 51086
Email: t.e.nichols 'at' warwick.ac.uk
Web: http://nisox.org
Blog: NISOx blog

[Book Cover]

Handbook of fMRI Data Analysis by Russ Poldrack, Thomas Nichols and Jeanette Mumford