Programme 



MONDAY 29th MARCH



09:00 - 10:00 Registration

   10:00 - 10:10 Welcome and Introduction

   10:10 - 11:10 Keynote Talk: Peter Donnelly, "Human recombination hotspots, evolution, and the PRDM9 gene"

   

   11:10 - 11:40 Tea/Coffee

   

   SESSION 1 Technologies I: Next-Generation Sequencing 

   11:40 - 12:00 Chris Greenman, "Estimating Rearrangment Evolution in Cancer with New Sequencing Technologies"

   12:00 - 12:20 Nicola De Maio, Carolin Kosiol, Andreas Futschik, Christian Schloetterer, "Estimation of population genetics parameters from pooled next generation sequencing data of Drosophila species"

   12:20 - 12:40 Klaudia Walter, Lorenz Wernisch and Matthew Hurles, "Genotyping Structural Variants from New Sequencing Technology Data"

   12:40 - 13:00 Thomas J. Hardcastle and Krystyna A. Kelly. "Empirical Bayesian methods for detecting patterns of differential expression in data acquired from high-throughput sequencing"

   

   13:00 - 14:00 Lunch

   

   SESSION 2 Technologies II: Next-Generation Sequencing, Bioimaging and Proteomics

   14:00 - 14:20 Alena Mysickova and and Martin Vingron, "Rank List Aggregation on Small RNA Digital Gene Expression Data"

   14:20 - 14:40 Juliane Liepe, "Quantitative imaging reveals p38 MAP kinase mediated chemotactic variability in leukocytes" 

   14:40 - 15:00 Michal Komorowski, "Approximate likelihood methods for quantitative single cell quantitative imaging data"

   15:00 - 15:20 Paul Kirk, "Robust Biomarker Discovery"

   

   15:20 - 15:50 Tea/Coffee and Posters

   

   SESSION 3 Genomics, Evolution and Sequence Analysis

   15:50 - 16:10 Catherine Higham, Christina Cobbold, Daniel Haydon, Darren Monckton, "A hierarchical Bayesian approach to quantify DNA instability in the inherited neuromuscular disease myotonic dystrophy"

   16:10 - 16:30 Sarah Behrens and Martin Vingron, "Studying the evolution of promoter sequences: a waiting time problem"

   16:30 - 16:50 Ryan Topping, William P. Kelly, Michael P.H. Stumpf and John W. Pinney, "Predictors of selection pressure across 39 strains of Saccharomyces cerevisiae"

   16:50 - 17:10 Rodrigo Liberal and John W. Pinney, "An evolutionary perspective on filling pathway holes"

   

   17:10 - 19:00 Drinks Reception, Posters

   Evening Conference Dinner

   

   



TUESDAY 30th MARCH



Session 4 Systems Biology I

   



 10:00 - 10:20 Yang Luo, Chia Lim, Alfonso Martinez-Arias and Lorenz Wernisch, "Modelling stochastic heterogeneity in cultures of stem cells" 



 10:20 - 10:40 Michalis Titsias, Antti Honkela, Magnus Rattray and Neil Lawrence, "Bayesian Inference of Multiple Transcription Factor Networks"



 



10:40 - 11:00 Frank Dondelinger, Sophie Lebre and Dirk Husmeier, "Inferring Developmental Gene Networks using Heterogeneous Dynamic Bayesian Networks with Information Sharing"





   11:00 - 11:30 Tea/Coffee and Posters



 

   Session 5 Systems Biology II





   



 11:30 - 11:40  Vote/Announcement of next MASAMB meeting

   11:40 - 12:00 Chris Barnes, "Efficient inference in systems biology models"

   12:00 - 12:20 William Kelly and Paul Kirk, "Stochastic Emulation of Biological Models"

   12:20 - 12:40 Daniel Silk, "Estimating Lyapunov exponents for biological systems in a Bayesian framework"

   

   12:40 Closing Statements

   

   12:40 - 13:40 Lunch

   

   13:45 LICSB workshop begins