Prof. Nigel Burroughs

You have reached the website of Nigel Burroughs in the Warwick Systems Biology Centre. I both teach, eg previously in the WSBC Systems Biology DTC and have a dynamic research group. I have very broad interests in applying physical science techniques (mathematics, physics, statistics) to biological and medical problems. I am predominantly stimulated by challenges in dynamic phenomena, either developing models of mechanism, or analysing data to demonstrate or discover mechanisms. This can be at a range of scales, from the molecular, eg a signalling mechanism, to the ecological, a predator-prey system (eg see Bee project), and use a variety of data types, 3+1D fluorescence data, omics data, biochemical data ..... I use a variety of techniques from mathematics and statistics, including dynamical systems, graph theory, stochastic modelling and the highly flexible range of Markov chain Monte Carlo techniques.

Research projects include/have included/hoped for- in cell biology: actin dynamics, microtubule dynamics, kinetochore oscillations (current project); in immunology: T cell and NK cell signalling; high dimensional omics data analysis: inferring gene regulatory networks by integrating transcriptome, proteome and bioinformatics data, (current projects include Bees and Nodules); in fluorescence data analysis: analysis of single particle tracking data, perturbation methods (Photoactivatable GFP, FRAP); in synthetic biology: improving photosynthesis (current project MAGIC); in Bioenergy: regulational aspects and design.

I run a small research group that fluctuates from 1-7 PDRAs, 1-4 PhD students. I hope they are happy and content.