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Dr Giorgos Minas

I joined WSBC in May 2013 after completing my PhD in Statistics at the Department of Statistics of University of Warwick. I worked as a Research Associate on PRESTA and ROBUST projects on modelling transcription regulation until April 2014. I currently hold the position of Research Fellow funded by the BBSRC research grant `Systems Biology analysis of biological timers and inflammation'. Our focus is on developing stochastic models for oscillatory systems (e.g. circadian clock, NF-κB) and constructing a framework for performing statistical inference and information theory analysis of the system through these stochastic models.

Publications

  • Minas, Giorgos and Rand, David A. Long-time analytic approximation of large stochastic oscillators: simulation, analysis and inference, Giorgos Minas and David A Rand bioRxiv (accepted PLos Comp Biology)
  • Minas, Giorgos and Dafyd J. and Rand, David A. and Finkenstädt, Bärbel (2017). Inferring transcriptional logic from multiple dynamic experiments, Bioinformatics, doi: 10.1093/bioinformatics/btx407
  • Minas, Giorgos and Momiji, Hiroshi and Jenkins, Dafyd J. and Costa, Maria J. and Rand, David A. and Finkenstädt, Bärbel (2017). ReTrOS: A MATLAB toolbox for reconstructing and analysing transcriptional activity from gene and protein expression data, BMC Bioinformatics, 18:316.
  • Multivariate Global Testing and Adaptive Designs. Minas, Giorgos, PhD Thesis 
  • Minas, Giorgos, Aston, John A. D. and Stallard, Nigel (2014). Adaptive multivariate global testing, Journal of the Americal Statistical Association (Theory and Methods), 109 (506): 613-623.
  • Minas, Giorgos, Rigat, Fabio, Nichols, Thomas E., Aston, John A. D. and Stallard, Nigel. A hybrid procedure for detecting global treatment effects in multivariate clinical trials: theory and applications to fMRI studies, Statistics in Medicine, 2012, 31, 253-268
  • Minas, Giorgos and Aston, John A. D (2013). Discussion on “Group sequential tests for delayed responses, L. V. Hampson and C. Jennisson, Journal of Royal Statistical Society, Series B (Statistical Methodology), 2013, 75, 3-54''
  • Minas, Giorgos, Aston, John A. D., Nichols, Thomas E. and Stallard, Nigel. ROI analysis of pharmafMRI data: an adaptive approach for global testing, Proceedings of 46th Scientific Meeting of the Italian Statistical Society, 2012

In preparation:

  • Binary and multi-component signalling in noisy biological systems
  • Statistical inference for oscillatory biological systems
Software:

TRS: Inferring transcriptional regulation logic from multiple dynamic experiments https://github.com/giorgosminas/TRS

ReTrOS: A MATLAB toolbox for reconstructing and analysing transcriptional activity from gene and protein expression data https://github.com/giorgosminas/ReTrOS

Selected Presentations
  • Rome, June, 2012: 46th Meeting of Italian Statistical Society, invited talk
  • London, May, 2012: RSS ordinary meeting, discussion
  • Warwick, January, 2012: Neurophysics Workshop, PharmafMRI, invited talk
  • Lancaster, June, 2011: Adaptive designs and multiple testing procedures Workshop, contributed talk
  • Warwick, May, 2011: Warwick Medical School Seminar, invited talk
  • Texas, January, 2011: Fourth Annual Bayesian Biostatistics Conference, contributed talk - poster
  • Piraeus, August, 2010: 28th European Meeting of Statisticians, contributed poster
  • Brighton, September 2010: Royal Statistical Society Conference, contributed talk

Other Academic Activities

Referee for Statistics in Medicine, Journal of Biopharmaceutical Statistics, Mathematical Reviews, Journal of Statistical Computation and Simulation

Teaching, Univ of Warwick:

- Lectures (4 classes replacement):

  • Bayesian Forecasting and Intervention, Spring Term 2016

- Supervision tutorials:

  • Mathematics and computational methods in systems biology (SYSMIC), Autumn term 2015

- Exercises tutorials:

  • Probability A-B, Spring Term 2010
  • Mathematical Statistics A-B, Autumn term 2010,2011, Spring Term 2012 \
  • Medical Statistics, Spring Term 2012

Reading Group organizer, Univ of Warwick:

  • Principles of Statistical Inference, Spring Term 2011
  • Neuroimaging Statistics, Academic Year 2011-2012

Contact details

Room 330, Warwick Systems Biology Centre, Senate House, University of Warwick, CV4 7AL

Tel (internal): 50243

Tel (external): +44 (0)24 76150243

Email address: giorgos.minas@warwick.ac.uk