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Dr. Jonathan (Jay) Moore
Senior Research Fellow in Bioinformatics
Tel: +44 777 625 3051
Email: jay.moore@warwick.ac.uk
Research interests
I am currently working within Warwick Systems Biology Centre specialising in data integration and evolutionary systems biology. I am collaborating on analysis of deep-sequencing data and am interested in developing integrations of pre/historical, geographical, biodiversity, and omics data.
I am developing bioinformatic approaches to understanding evolution of response to environmental stress in Arabidopsis and metabolic switching in Streptomyces coelicolor . I am on the PALS group of the SYSMO programme, developing common approaches to bioinformatics for the systems biology of microorganisms. I am an honorary member of the Allaby Research Group which specialises in plant evolution and crop domestication, with whom I developed the TreeMos application to identify and visualise phylogenetic mosaicism. I maintain an ongoing interest in developing comparative models of genome organisation in Brassicaceae.
Biography
Ph.D. Plant and Environmental Science, University of Warwick Constraints on sequence evolution in the segmentally duplicated Brassica oleracea genome
M.Sc. Conservation and Utilisation of Plant Genetic Resources (Distinction), University of Birmingham
P.G.Cert. Enterprise and Network Management, Sheffield Hallam University
B.Eng. (Hons.) Electronic Engineering, University of Sheffield
I have provided leadership in a variety of collaborative online projects, including curation of the ScoCyc database of Streptomyces metabolic pathways, and in the past managing the development of the online Journal of International Wildlife Law and Policy, and working for the Open University as an Associate Lecturer and Team Leader in piloting their first online course. I also provided technical leadership to the European Crop Wild Relative Diversity Assessment and Conservation Forum, and was responsible for database design and development of the forum's Crop Wild Relative Information System CWRIS, an online database of the Crop Wild Relatives of Europe and the Mediterranean.
I have worked as a consultant for a variety of international management consultancy companies and public sector organisations through my own business, providing technical leadership in large-scale data integration projects.
I also manage and edit GardenTalk.co.uk.
Recent publications
- Nieselt, K., Battke, F., Herbig, A., Bruheim, P., Wentzel, A., Jakobsen, O.M., Sletta, H., Alam, M.T., Merlo, M.E., Moore, J., Omara,W., Morrissey, E.R., Juarez-Hermosillo, M., Rodríguez-García, A., Nentwich, M., Thomas, L., Legaie, R., Gaze, W.H., Challis, G.L., Jansen, R.C., Dijkhuizen, L., Rand, D.A., Wild, D.L., Bonin, M., Reuther, J., Wohlleben, W., Smith, M.C.M., Burroughs, N.J., Martín, J.F., Hodgson, D.A., Takano, E., Breitling, R., Ellingsen, T.E., Elizabeth M. H. Wellington, E.M.H. (2010) The dynamic architecture of the metabolic switch in Streptomyces coelicolor. BMC Genomics 11:10
- Palmer, S.A., Moore, J.D., Clapham, A.J., Rose, P. and Allaby, R.G. (2009) Archaeogenetic Evidence of Ancient Nubian Barley Evolution from Six to Two-Row Indicates Local Adaptation. PLoS ONE 4(7): e6301.
- Alix, K., Joets, J., Ryder, C.D., Moore, J., Barker, G.C., Bailey, J.P., King, G.J. and Heslop-Harrison, J.S. (2008) The CACTA transposon Bot1 played a major role in Brassica genome divergence and gene proliferation. The Plant Journal 56: 1030-1044
- Moore, J.D., Kell, S.P., Iriondo J, Ford-Lloyd, B. and Maxted, N. (2008) CWRML: representing crop wild relative conservation and use data in XML. BMC Bioinformatics 9:116.
- Moore, J.D. and Allaby, R.G. (2008) TreeMos: a high-throughput phylogenomic approach to find and visualise phylogenetic mosaicism. Bioinformatics 24(5):717-718.
- Kell, S.P., Moore, J.D., Iriondo, J.M., Scholten, M.A., Ford-Lloyd, B.V. and Maxted, N. (2008) CWRIS: an information management system to aid crop wild relative conservation and sustainable use. In: Maxted, N., Ford-Lloyd, B.V., Kell, S.P., Iriondo, J., Dulloo, E. and Turok, J. (eds.) Crop Wild Relative Conservation and Use. CABI Publishing, Wallingford. Pp. 469-489.
- Alix, K., Ryder, C.D., Moore, J., King, G.J., and Heslop-Harrison, P.J.S. (2005). The Genomic Organization of Retrotransposons in Brassica oleracea. Plant Molecular Biology 59:6 839-851.
- Kell, S.P., and Moore, J. (2005). The PGR Forum crop wild relative information system (CWRIS): an introduction. Crop Wild Relative 4: 4-5.
- Moore, J.D. and Kell, S.P. (eds.) (2005). PGR Forum CD ROM. University of Birmingham, UK.
Conference presentations
- Bari, M.F., Moore, J., Zehnder, D., Bird, H., and Snead, D. (2010). Analysis of gene expression array data to identify biomarkers specific to small cell lung cancer. Poster Presentation. AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer 2010, Coronado, USA.
- Bari, M.F., Moore, J., Zehnder, D., Bird, H., and Snead, D. (2010). Molecular Characteristics of Small Cell Lung Carcinoma. Pathological Society of Great Britain and Ireland Winter Meeting, London, UK.
- Moore, J.D. and Allaby R.G. (2008). TreeMos: a high-throughput phylogenomic approach to identifying and visualising phylogenetic mosaicism. Poster Presentation. Genetics 2008, Berlin, Germany.
- Alix, K., Ryder, C.D., Moore, J., King, G.J. and Heslop-Harrison, P.J.S. (2006). The Diversity And Organization Of Retrotransposons In Brassica: Understanding Their Phylogeny And Evolution. Poster presentation. In: Plant and Animal Genome XIV Conference Abstracts.
- Moore, J.D., King, G.J., Lynn, J. (2006). Data integration for Brassica comparative genomics. Oral presentation. 2006 UK Brassica Research Community Annual Meeting, John Innes Centre, UK.
- Barker, G., Ryder, C., Moore, J., Weaver, G., Naylor, R., Edwards, R., Sharpe, A., Durkin, J., Lydiate, D., and King, G. (2005). EST Sequencing of Brassica oleracea. Poster presentation. In: Plant and Animal Genome XIII Conference Abstracts.
- Kell, S.P., Moore, J., Iriondo, J.M., Scholten, M.A. and Maxted, N. (2005). Creation and development of the PGR Forum CWR Information System (CWRIS). Oral presentation. In: First International Conference on Crop Wild Relative Conservation and Use: Book of abstracts (Kell, S., Scholten, M. eds.).
- Barker, G., Ryder, C., Moore, J., Naylor, R., Edwards, R., Sharpe, A., Durkin, J., Lydiate, D., and King, G. (2004). A public EST sequencing programme for Brassica oleracea. Poster presentation. Brassica 2004, Daejeon, Korea.
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