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Professor Sascha Ott - Recent Publications

Wordle endometriosis

Single-cell analysis identifies distinct macrophage phenotypes associated with pro-disease and pro-resolving functions in the endometriotic niche”, Yasmin Henlon, Kavita Panir, Iona McIntyre, Chloe Hogg, Priya Dhami, Antonia O Cuff, Anna Senior, Niky Moolchandani-Adwani, Elise T Courtois, Andrew W Horne, Matthew Rosser, Sascha Ott, Erin Greaves, bioRxiv, 2024


Wordle pancreatic cancer paper

Analysis of single nuclear chromatin accessibility reveals unique myeloid populations in human pancreatic ductal adenocarcinoma”, Hillary G. Pratt, Li Ma, Sebastian A. Dziadowicz, Sascha Ott, Thomas Whalley, Barbara Szomolay, Timothy D. Eubank, Gangqing Hu, Brian A. Boone, Clinical and Translational Medicine, 14: e1595, 2024


TimeTeller

TimeTeller: A tool to probe the circadian clock as a multigene dynamical system”, Denise Vlachou , Maria Veretennikova, Laura Usselmann , Vadim Vasilyev, Sascha Ott, Georg A. Bjarnason, Robert Dallmann, Francis Levi, David A. Rand, PLOS Computational Biology, 20: e1011779, 2024


scATAC Wordle

"Dynamic chromatin remodeling in cycling human endometrium at single-cell level”, Pavle Vrljicak, Emma S. Lucas, Maria Tryfonos, Joanne Muter, Sascha Ott, Jan J. Brosens, Cell Reports, 42: 113525, 2023


Rhizobia Wordle

Rhizobial nitrogen fixation efficiency shapes endosphere bacterial communities and Medicago truncatula host growth”, Beatriz Lagunas, Luke Richards, Chrysi Sergaki, Jamie Burgess, Alonso Javier Pardal, Rana M.F. Hussain, Bethany L. Richmond, Laura Baxter, Proyash Roy, Anastasia Pakidi, Gina Stovold, Saúl Vázquez, Sascha Ott, Patrick Schäfer, Miriam L. Gifford, Microbiome, 11: 146, 2023


Gata2 Wordle

Lineage skewing and genome instability underlie marrow failure in a zebrafish model of GATA2 deficiency”, Christopher B. Mahony, Lucy Copper, Pavle Vrljicak, Boris Noyvert, Chrystala Constantinidou, Sofia Browne, Yi Pan, Claire Palles, Sascha Ott, Martin R. Higgs, Rui Monteiro, Cell Reports, 42: 112571, 2023


hotspots

Properties of non-coding mutation hotspots as urinary biomarkers for bladder cancer detection”, L. Baxter, N.S. Gordon, S. Ott, J. Wang, P. Patel, A. Goel, K. Piechocki, L. Silcock, C. Sale, M.P. Zeegers, K.K. Cheng, N.D. James, The BladderPath trial management group, R.T. Bryan, D.G. Ward, Scientific Reports, 13: 1060, 2023


CDD

Epigenetic priming of immune/inflammatory pathways activation and abnormal activity of cell cycle pathway in a perinatal model of white matter injury”, Anne-Laure Schang, Juliette Van Steenwinckel, Zoi S. Ioannidou, Julia Lipecki, Charlotte Rich-Griffin, Kate Woolley-Allen, Nigel Dyer, Tifenn Le Charpentier, Patrick Schäfer, Bobbi Fleiss, Sascha Ott, Délara Sabéran-Djoneidi, Valérie Mezger, Pierre Gressens, Cell Death & Disease, 13: 1038, 2022


Inform-Bladder

"Highly Sensitive and Specific Detection of Bladder Cancer via Targeted Ultra-deep Sequencing of Urinary DNA”, Douglas G Ward, Laura Baxter, Sascha Ott, Naheema S Gordon, Junhui Wang, Prashant Patel, Kim Piechocki, Lee Silcock, Chris Sale, Maurice P Zeegers, K K Cheng, Nicholas D James, Richard T Bryan, BladderPath Trial Management Group, European Urology Oncology, 6: 67-75, 2022


Methylation paper

Immediate perturbation of DNA methylation upon acute prenatal alcohol exposure in the mouse developing brain cortex”, Agathe Duchateau, Névé Auperin, Federico Miozzo, Anne Le Mouel, Olivier Kirsh, Myriame Mohamed, Sascha Ott, Délara Saberan-Djoneidi, Valérie Mezger, bioRxiv, 2022


EndoTime Wordle

EndoTime: Non-categorical timing estimates for luteal endometrium”, Julia Lipecki, Andrew E Mitchell, Jo Muter, Emma S Lucas, Komal Makwana, Katherine Fishwick, Joshua Odendaal, Amelia Hawkes, Pavle Vrljicak, Jan J Brosens, Sascha Ott, Human Reproduction, 37: 747–761, 2022


PDAC Wordle

Macrophage and Neutrophil Interactions in the Pancreatic Tumor Microenvironment Drive the Pathogenesis of Pancreatic Cancer”, Hillary G Pratt, Kayla J Steinberger, Nicole E Mihalik, Sascha Ott, Thomas Whalley, Barbara Szomolay, Brian A Boone, Timothy D Eubank, Cancers, 14: 194, 2022