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GeneSys programme - room B 3.02

Monday 21.09 Morning

09.00-10.00 ECCS Welcome address

10.00-10.30 coffee

Tutorials: introduction to Genetical Genomics and network inference. These tutorials are aimed to introduce the area of the GENESYS workshop and provide a start point for the rest of the meeting.

10:30-11.30 Tutorial on eQTL by Enrico Petretto, Imperial College, London

11:30-12:30 Tutorial on gene networks by Ernst Wit, Groningen University

12.30-14.00 Lunch

Monday 21.09 Afternoon

14:00-15.00 Keynote: Rebecca Doerge, Purdue University
"Gene networks from eQTL; are we there yet?"

15:00-15:20 break

15:20-16.00 Nico Katsanis, John Hopkins University School of Medicine
16:00 - 17:00 Tea + posters


Tuesday 22.09 Morning

09.00-10.00 ECCS plenary session

10.00-10.30 coffee

10:30-11.10 Ernst Wit, Groningen University
``Modelling networks: top-down or bottom-up?''

11:10-11:50 Guido Sanguinetti, University of Sheffield
“Reverse engineering switching transcription factor activities from microarray data”
11:50-12:20 contributed: Andrea Rau, Purdue University
“Reverse-Engineering Gene Regulatory Networks From Microarray Data with Dynamic Bayesian Network”

12:20-12:30 Discussion

12.30-14.00 Lunch

Tuesday 22.09 Afternoon

14:00-14:40 Rosalind Allen, University of Edinburgh
Simulating the bacteriophage lambda genetic switch

14:40-15.20 Tamas Dalmay, University of East Anglia
Experimental target identification of microRNA-140

15:20-16.00 Matt Rockmann, New York Univeristy
Genetic causes of transcript abundance variation in C. elegans
16:00 - 17:00 Tea + posters

Wednesday 23.09 morning

09:00-09:40 Arne Gjuvsland, Cigene
Causally cohesive genotype-phenotype models - systems biology meets genetics

09:40-10:10 contributed: Yang Li, Groningen University
“Causal inference in genome-wide association and linkage studies: a quantitative genetic perspective”

10:10-10:30 Coffee break

10:30-11.10 Sacha Ott, Warwick University
Transcriptional regulatory networks from the viewpoint of sequence analysis
11:10-11.40 Contributed: Matthieu Vignes. INRA
“From gene clustering to genetical genomics: using or reconstructing biological networks”
11.40- 12.30 General discussion and closure

Register for ECCS09 at

Call for Abstracts:
Submit Poster abstracts via ECCS09 web link:
(choose GENESYS, deadline 1/9!)


The goal of the GENESYS network is to promote the required integration between genetics, bioinformatics and mathematics to facilitate the reverse-engineering of regulatory networks using genetic mapping data and high throughput data, such as transcriptomics. This is an important step toward systems biology approaches where these regulatory networks will be refined and evolve into quantitative models of regulation.

The GeneSys coordinators:

DJ de Koning, The Roslin Institute and R(D)SVS, University of Edinburgh
Chris Haley, MRC Human Genetics Unit and The Roslin Institute
Tim Aitman, MRC Clinical Sciences Centre and Imperial College, London
Arnis Druka and Robbie Waugh, Scottish Crops Research Institute, Dundee
John Whittaker, GlaxoSmithKline, Harlow
Dirk Husmeier, Biomathematics and Statistics Scotland, Edinburgh
Chris Rawlings, Rothamsted Research, Harpenden