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Colon cancer; peptide-mimetic metal helices
Warwick chemists Becky Kaner and Alan Faulkner, working with other members of the Scott research group, have developed a unique asymmetric self-assembly which delivers optically pure triplex helicates. The molecules, based on helical arrays of small organic molecules around a core of Fe(II) ions, have amphipathic structures like host-defence peptides, and they act as highly potent and highly selective anticancer compounds. The work is published in Nature Chemistry.