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Prof. Andrew Dove


Prof Andrew P. Dove

Professor of Chemistry

MChem (York), PhD (Imperial)



Research Summary

The Dove group focus on the synthesis and application of degradable biomaterials and sustainable polymers. This work includes: Organocatalyzed polymerisation; click chemistry for polymer synthesis and modification; application of sustainable/green chemistries and building blocks for polymer sythesis; as well as the fabrication, understanding and control over properties of new biomaterials on all length scales from macroscopic mechanical and biological properties to 3-dimensional control of structure at the micron level as well as the controlled nanoscale assembly. In turn, these studies are focussed in the development of novel hydrogels, elastomers, scaffolds and nanoparticles for tissue engineering, regenerative medicine and drug/gene delivery applications. The group has a particular interest in the application of stereochemistry in materials science.


Selected Publications

Dual Catalysis for Selective Ring-Opening Polymerization of Lactones: Evolution toward Simplicity. Naumann, S.; Scholten, P. B. V.; Wilson, J. A.; Dove, A. P.; J. Am. Chem. Soc. 2015 137, 14439–14445.

N-Heterocyclic Olefins as Organocatalysts for Polymerization: Preparation of Well-Defined Poly(propylene oxide). Naumann, S.; Thomas, A. W.; Dove, A. P.; Angew Chem. Int. Ed. 2015, 54, 9550 - 9554.

Simultaneous orthogonal dual-click approach to tough, in situ-forming hydrogels for cell encapsulation. Truong, V. X.; Ablett, M. P.; Richardson, S. M.; Hoyland, J. A.; Dove, A. P. J. Am. Chem. Soc. 2015, 137, 1618 - 1622.

Structural reorganization of cylindrical nanoparticles triggered by polylactide stereocomplexation. Sun, L; Pitto-Barry, A.; Kirby, N.; Schiller, T. L.; Sanchez, A. M.; Dyson, M. A.; Sloan, J.; Wilson, N. R.; O’Reilly R. K.; Dove A. P. Nature Commun. 2014 5:5746

Organocatalytic, Regioselective Nucleophilic “Click” Addition of Thiols to Propiolic Acid Esters for Polymer–Polymer Coupling Truong, V. X.; Dove, A. P. Angew. Chem. Int. Ed. 2013, 52, 4132 - 4136

Benzyl Bispidine as an Efficient Replacement for (-)-Sparteine in Ring Opening Polymerisation. Todd, R.; Rubio, G.; Hall, D. J.; Tempelaar, S.; Dove, A. P.; Chem. Sci. 2013, 4, 1092 - 1097.