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Selected publications


Transfer hydrogenation catalysis in cells as a new approach to anticancer drug design

J.J. Soldevila-Barreda1, I. Romero-Canelón1, A. Habtemariam, P.J. Sadler

Nature Commun. 2015, in press. 1 Both authors contributed equally to this work


Fabrication of crystals from single metal atoms

N.P.E. Barry, A. Pitto-Barry, A.M. Sanchez, A.P. Dove, R.J. Procter, J.J. Soldevila-Barreda, N. Kirby, I. Hands-Portman, C.J. Smith, R.K. O’Reilly, R. Beanland, P.J. Sadler

Nature Commun. 2014, 5:3851 | DOI: 10.1038/ncomms4851


Potent organometallic osmium compounds induce mitochondria-mediated apoptosis and S-phase cell cycle arrest in A549 non-small cell lung cancer cells

S.H. van Rijt, I. Romero-Canelón, Y. Fu, S.D. Shnyder, P.J. Sadler

Metalllomics 2014, 6, 1014-1022. Selected Hot Article


Cellular Accumulation, Lipophilicity and Photocytotoxicity of Diazido Platinum(IV) Anticancer Complexes

A.M. Pizarro, R.J. McQuitty, F.S. Mackay, Y. Zhao, J.A. Woods, P.J. Sadler

ChemMedChem 2014, 9, 1169-1175.


Insights into the Binding Sites of Organometallic Ruthenium Anticancer Compounds on

Peptides Using Ultra-High Resolution Mass Spectrometry

R.H. Wills, A. Habtemariam, A.F. Lopez-Clavijo, M.P. Barrow, P.J. Sadler, P.B. O’Connor


J. Am. Soc. Mass Spectrom. 2014, 25, 662-672.



100 Years of Metal Coordination Chemistry: from Alfred Werner to Anticancer Metallodrugs

N.P.E. Barry, P.J. Sadler

Pure & Applied Chem. 2014, 86, 1897–1910.


The Potent Oxidant Anticancer Activity of Organoiridium Catalysts.

Z. Liu, I. Romero-Canelón; B. Qamar, J.M.Hearn, A. Habtemariam, N.P.E. Barry, A.M. Pizarro,

G.J. Clarkson, P.J. Sadler

Angew. Chem., Int. Ed. 2014, 53, 3941–3946. Selected VIP