Antibiotic Chemotherapy: Computational design, Synthesis and testing of novel amino acid ATP ligase inhibitors

Miniproject 1: Molecular modelling of MurC amino acid ligase

Supervisors:

Centre for Scientific Computing, University of Warwick

• Professor Mark Rodger

MRCT, Mill Hill, London

• Dr Jasveen Chugh

Miniproject 2: Synthesis of novel ATP ligase inhibitors

Supervisor:

Chemical Biology, University of Warwick

• Professor Tim Bugg

Miniproject 3: Functional characterisation of these potential ATP ligase inhibitors

Supervisors:

Biological Sciences, University of Warwick

• Professor Chris Dowson
• Dr David Roper
• Dr Adrian Lloyd