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Philip Law

Education

2002-2004

BSc (Biochemistry and Computer Science) Rand Afrikaans University, now University of Johannesburg, South Africa
2005 BSc Hons (Bioinformatics) University of Pretoria, South Africa
2006-2008 MSc (Bioinformatics)

University of Pretoria, South Africa

2009-2010 MSc (Systems Biology) University of Warwick



MSc

Mini-project 1

My first mini-project was supervised by Andrew Mead and involved fitting nonlinear curves to model genes' expression levels from time series microarray data. Poster(PDF Document)


Mini-Project 2

The second mini-project was supervised by Claire Hill, and involved using yeast 1-hybrid assays to identify the regulators of Arabidopsis genes that are involved during Botrytis cinerea infection. Poster(PDF Document)


PhD

My PhD project is titled "Quantitative Analysis of Time-Series Microarray Data to Predict Responses to Environmental Stresses in Arabidopsis", and supervised by Andrew Mead and Vicky Buchanan-Wollaston.

It is an extension of the first mini-project, and is involved in analysing data from the PRESTA project, by fitting parametric nonlinear curve shapes to the gene expression data.

By then applying a number of goodness-of-fit statistics, the best fitting shape can be found. Clustering on these parameters will potentially allow for the identification of genes that are involved in similar biological processes.

Poster from the 2010 DTC Conference(PDF Document)



Conferences Attended

2011 - Inter-DTC conference, Manchester (poster)

2012 - Postgraduate Life Sciences Symposium, Warwick (poster)

2012 - Inter-DTC conference, Oxford (poster)

August 2012 - International Biometric Conference, Kobe, Japan (presentation)

March 2013 - Postgraduate Life Sciences Symposium, Warwick (presentation) - Prezi

May 2013 - id2 conference, UCL, London (presentation)

June 2013 - Annual Conference, Stratford (presentation) - Prezi

July 2013 - Channel Network Conference, St Andrews, Scotland (presentation)


Other Activities

I am one of the SSLC (Student-Staff Liason Commitee) representatives for this year group, along with Kate Richardson.

From 2010-2012, I was the Secretary of the Systems Biology SSLC.


Previous Work

My previous MSc project in Pretoria: MADIBA (MicroArray Data Interface for Biological Interpretation) - http://www.bi.up.ac.za/MADIBA/

Law PJ, Claudel-Renard C, Joubert F, Louw AI and Berger DK (2008) MADIBA: A web server toolkit for biological interpretation of Plasmodium and plant gene clusters, BMC Genomics 9:105

Naidoo S, Fouché-Weich J, Law P, Denby K, Marco Y and Berger DK (2011) A Eucalyptus bacterial wilt isolate from South Africa is pathogenic on Arabidopsis and manipulates host defenses, Forest Pathology 41(2):101-113

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Philip Law

Coventry House

University of Warwick

Coventry

CV4 7AL

P.J.Law AT warwick DOT ac DOT uk