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CRiSM Seminar - Federico Turkheimer (Imperial)

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Location: A1.01
Federico Turkheimer (Imperial)

Title: Higher Mental Ability: A Matter of Persistence?
Abstract: Executive function is thought to originate in the dynamics of frontal cortical networks of the human brain. We examined the dynamic properties of the blood oxygen level-dependent (BOLD) time-series measured with fMRI within the prefrontal cortex to test the hypothesis that temporally persistent neural activity underlies executive performance in normal controls doing executive tasks. A numerical estimate of signal persistence, derived from wavelet scalograms of the BOLD time-series and postulated to represent the coherent firing of cortical networks, was determined and correlated with task performance. We further tested our hypothesis on traumatic brain injury subjects that present with mild diffuse heterogenous injury but common executive dysfunction, this time using a resting state experimental condition.

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