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CRiSM Seminar - Vincent Macaulay (Glasgow)

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Location: A1.01
Vincent Macaulay, Dept of Statistics, University of Glasgow
Inference of migration episodes from modern DNA sequence variation
One view of human prehistory is of a set of punctuated migration events across space and time, associated with settlement, resettlement and discrete phases of immigration. It is pertinent to ask whether the variability that exists in the DNA sequences of samples of people living now, something which can be relatively easily measured, can be used to fit and test such models. Population genetics theory already makes predictions of patterns of genetic variation under certain very simple models of prehistoric demography. In this presentation I will describe an alternative, but still quite simple, model designed to capture more aspects of human prehistory of interest to the archaeologist, show how it can be rephrased as a mixture model, and illustrate the kinds of inferences that can be made on a real data set, taking a Bayesian approach.

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