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Sarah-Jane Richards

PREVIOUS EDUCATION

I have an MChem degree in Chemistry from The University of Sheffield. My Fourth year project was entitled 'Smart Polymers for Improved Oil and Gas Production'. I used fluorescence anisotropy techniques to investigate the dynamics of thermoresponsive polymers for their use in clatherate hydrate inhibition.

MOAC

I joined MOAC in 2010 to carry out an MSc in Mathematical Biology and Biophysical Chemistry.


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During my MSc I completed 3 mini-projects. For more details about the projects use the links below:

  • Mini-Project 1 - Molecular Dynamics Investigation of Biomimetic Antifreeze Macromolecules.
  • Mini-Project 2 - Cloning and expression of transcriptional repressors in Escherichia coli.
  • Mini-Project 3 - Inhibiting Bacterial Toxin Recognition at Model Cell Membranes.

My PhD is entitled Glycosylated nanomaterials: Neutralisation and detection of bacteria and toxins.

PUBLICATIONS

[11] Richards, S-J., Otten, L., Gibson, M. I, Submitted

[10] Richards, S-J., Biggs, C. I., Gibson, M. I., Invited book chapter Submitted

[9] Richards, S-J. and Gibson, M.I., ACS Macro Lett., 2014, 3, 1004-1008. 'Optimization of the Polymer Coating for Glycosylated Gold Nanoparticle Biosensors to Ensure Stability and Rapid Optical Readouts"

[8] Richards, S-J., Fullam, E.C., Besra, G.S., Gibson, M.I., J. Mater. Chem. B., 2014, 2, 1490 "Discrimination between bacterial phenotypes using glyco-nanoparticles and the impact of polymer coating on detection readouts"

[7] Jones, M.W., Otten, L., Richards, S-J., Lowery, R., Phillips D.J., Haddleton D.M., and Gibson M.I. Chem. Sci., 2014, 5, 1611 "Glycopolymers with secondary binding motifs mimic glycan branching and display bacterial lectin selectivity in addition to affinity"

[6] Lu, J., Zhang, W., Richards, S-J., Gibson, M.I., Chen, G. Polym. Chem., "Glycopolymer-coated Gold Nanorods Synthesized by a One Pot Copper(0) Catalyzed Tandem RAFT/Click Reaction" 2013, DOI: 10.1039/C3PY01526B

[5] Gou, Y.; Geng, J; Richards, S-J.; Burns, J.; Becer, C. R.; Haddelton, D. M.; Journal of Polymer Science, Part A: Polymer Chemistry, 2013, 51, 2588–2597 "A Detailed Study on Understanding Glycopolymer Library and Con A Interactions' link Featured on the front cover of the journal." link Featured on the front cover of the journal

[4] Otten, L., Richards, S-J., Fullam, E., Besra, G.S., Gibson, M.I., 2013, Journal of Materials Chemistry B. "Gold Nanoparticle-Linked Analysis of Carbohydrate-Protein Interactions, and Polymeric Inhibitors, using Unlabelled Proteins; Easy Measurements Using a ‘Simple’ Digital Camera" link

[3] Jones, M.W., Richards, S-J., Haddleton, D.M., Gibson M.I., Polymer Chemistry, Advance article, 2013, DOI: 10.1039/C2PY20757E, "Poly(Azlactone)s: Versatile Scaffolds for Tandem Post-Polymerisation Modification and Glycopolymer Synthesis" link  3rd most accessed article October 2012

[2] Richards, S-J., Jones, M.W., Hunaban, M., Haddleton, D.M., Gibson, M.I., Angewandte Chemie. International Edition., 2012, 51, 7812 - 7816. "Probing Bacterial Toxin Inhibition with Synthetic Glycopolymers using Tandem Post-Polymerization Modification: Role of Linker and Carbohydrate Density" link

[1] Gou, Y., Richards, S-J., Haddleton, D.M., Gibson, M.I., Polymer Chemistry, 2012, 3, 1634 - 1640. "Investigation of Glycopolymer-Lectin Interactions using QCM-d: Comparison of Surface Binding with Inhibitory Activity" link

MChem Sheffield Graduation Photo

CONTACT DETAILS
S-J dot Richards at Warwick dot ac dot uk
MOAC DTC
The University of Warwick
Coventry House
Coventry
CV4 7AL